{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:33:12Z","timestamp":1787646792731,"version":"build-2736575974"},"reference-count":36,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T00:00:00Z","timestamp":1714435200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2025,2]]},"abstract":"<jats:p>Malakoplakia is a rare disease that manifests as a histiocytic inflammatory process and most often occurs in the urinary bladder. It is caused by an impaired capacity of histiocytes to kill and digest bacteria. The typical histopathologic findings are sheets of histiocytes with granular eosinophilic cytoplasm and characteristic Michaelis\u2013Gutmann bodies, spherical bodies with a targetoid appearance. Malakoplakia is even rarer in the gynecologic tract, and our literature search found only 21 published patients of malakoplakia involving the endometrium. Here we report a 60-year-old female patient who presented with recurrent pelvic infections and postmenopausal bleeding, which raised concern for an endometrial malignancy. Hysterectomy with salpingo-oophorectomy revealed malakoplakia involving the endometrium and also the right ovary. Michaelis\u2013Gutmann bodies were visible on the intraoperative frozen section that was performed to rule out an endometrial malignancy. We summarize the clinicopathologic findings of the published patients of endometrial malakoplakia.<\/jats:p>","DOI":"10.1177\/10668969241248581","type":"journal-article","created":{"date-parts":[[2024,5,1]],"date-time":"2024-05-01T01:16:22Z","timestamp":1714526182000},"page":"189-194","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Malakoplakia of the Endometrium: A Rare Unexpected Disease Raising Clinical Concern for Malignancy"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8238-3134","authenticated-orcid":false,"given":"Edgar G.","family":"Fischer","sequence":"first","affiliation":[{"name":"Division of Surgical Pathology and Cytopathology, Department of Pathology, University of New Mexico, Albuquerque, NM, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devin E.","family":"Jones","sequence":"additional","affiliation":[{"name":"Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emily S.","family":"Wu","sequence":"additional","affiliation":[{"name":"Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teresa L.","family":"Rutledge","sequence":"additional","affiliation":[{"name":"Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of New Mexico Comprehensive Cancer Center, Albuquerque, NM, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,4,30]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"208","article-title":"\u00dcber Einschl\u00fcsse in Blasentumoren","volume":"47","author":"Michaelis L","year":"1902","unstructured":"Michaelis L, Gutmann C. \u00dcber Einschl\u00fcsse in Blasentumoren. Z Klin Med. 1902;47:208.","journal-title":"Z Klin Med"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/BF01944507"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-54941-7.00005-0"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(98)00130-2"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(74)80066-3"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197712292972601"},{"issue":"2","key":"e_1_3_2_8_2","first-page":"177","article-title":"Ultrastructural evidence of the evolutional process in malakoplakia","volume":"35","author":"Jung YS","year":"2020","unstructured":"Jung YS, Chung DY, Kim EJ, Cho NH. Ultrastructural evidence of the evolutional process in malakoplakia. 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Obstet Gynecol. 1985;65(3 Suppl):84S-87S.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/00004347-200110000-00016"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-46334-6_7"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1093\/ajcp\/aqab191.168"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1016\/0028-2243(85)90018-8"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.19245"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-020-01014-x"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.5795\/jjscc.52.139"},{"issue":"5","key":"e_1_3_2_19_2","first-page":"585","article-title":"[Malacoplakia in the endometrium. A rare cause of postmenopausal bleeding]","volume":"113","author":"Haugeberg G","year":"1993","unstructured":"Haugeberg G, Solberg LA, Qvigstad E. [Malacoplakia in the endometrium. 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