{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:28:15Z","timestamp":1787646495421,"version":"build-2736575974"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>While the presence of adipose tissue and its involvement by prostatic cancer (extraprostatic extension) is well-recognized in prostate biopsies, adipose tissue in transurethral resections of the prostate (TURP) is largely unexplored. Herein, 200 consecutive TURPs and related specimens were reviewed, including a separate 3-year analysis of specimens containing prostatic cancer, with the following data collected: presence of fat, presence of cancer within fat, and quantity of fat. For specimens with both fat and prostatic cancer, specimen weight and tumor volume were recorded. Within the 200 consecutive TURPs and related specimens, adipose tissue was identified in 20%; 55% had 2.5 mm of adipose tissue; the number of fragments with adipose tissue ranged from 1 to 14. No correlation between specimen weight and measured extent of adipose tissue or number of fragments with adipose tissue was identified. Of all the specimens with prostatic cancer, 15\/56 (27%) involved adipose tissue, with two specimens with large cancer volume (&gt;90%) demonstrating extensive involvement of adipose tissue. Adipose tissue is frequently present within TURP and related specimens with variability in extent. The etiology behind encountering adipose tissue is uncertain, and it could represent resection into peri-prostatic fat, intraprostatic fat, or bladder neck fat sampling. Although encountering adipose tissue involved by cancer in TURP and related specimens may imply extraprostatic extension (pT3a), further studies are needed to corroborate these findings as well as to determine if these should be included in reported synoptics.<\/jats:p>","DOI":"10.1177\/10668969241265032","type":"journal-article","created":{"date-parts":[[2024,8,2]],"date-time":"2024-08-02T00:43:51Z","timestamp":1722559431000},"page":"375-383","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Incidence and Pitfalls of Adipose Tissue Encountered in Prostatic Transurethral Resections and Related Specimens"],"prefix":"10.1177","volume":"33","author":[{"given":"Douglas Jian-Xian","family":"Wu","sequence":"first","affiliation":[{"name":"Stanford Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James D.","family":"Brooks","sequence":"additional","affiliation":[{"name":"Stanford Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carol","family":"Rizkalla","sequence":"additional","affiliation":[{"name":"University of Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0874-8964","authenticated-orcid":false,"given":"Ankur R.","family":"Sangoi","sequence":"additional","affiliation":[{"name":"Stanford Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,1]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21708"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6941a1"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2009.09110.x"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2016.03.152"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2018.10.023"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2017.167"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2008.10.004"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2559.2009.03299.x"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2003.12.003"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0046-8177(98)90129-0"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1080\/00313020600820914"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/10668969221133349"},{"key":"e_1_3_2_14_2","unstructured":"Paner GP Srigley JR Zhou M et al. College of American Pathologists: Protocol for the Examination of Radical Prostatectomy Specimens From Patients With Carcinoma of the Prostate Gland 4.0.4.0; College of American Pathologists. 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College of American Pathologists: Protocol for the Examination of TURP and Enucleation Specimens From Patients With Carcinoma of the Prostate Gland Version 4.2.0.0; College of American Pathologists. 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