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We present two primary visceral Ewing sarcomas confirmed at the molecular level: one located in the stomach and the other in the bladder. Both tumors demonstrated strong and diffuse membranous CD99 expression, accompanied by variable KIT immunoreactivity. Additionally, we provide a review of the literature on primary gastric and bladder ES, including an analysis of differential diagnoses for gastric and bladder tumors exhibiting CD99 and KIT expression.<\/jats:p>","DOI":"10.1177\/10668969241308205","type":"journal-article","created":{"date-parts":[[2025,1,29]],"date-time":"2025-01-29T12:56:50Z","timestamp":1738155410000},"page":"1299-1316","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Primary Visceral Ewing Sarcoma (Gastric and Bladder) with KIT Expression: A Report of Two Patients and a Differential Diagnostic Approach"],"prefix":"10.1177","volume":"33","author":[{"given":"Anas","family":"Chaachou-Charradi","sequence":"first","affiliation":[{"name":"Pathology Department, Hospital Arnau de Vilanova, Valencia, Spain"},{"name":"Pathology Department, Vall d\u2019Hebron University Hospital, Barcelona, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Bagu\u00e9","sequence":"additional","affiliation":[{"name":"Hospital de la Santa Creu i Sant Pau"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carmen Medina","family":"Medina","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital Arnau de Vilanova, Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javier","family":"Lavernia","sequence":"additional","affiliation":[{"name":"Medical Oncology Department, Instituto Valenciano de Oncolog\u00eda (IVO), Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Reyes","family":"Claramunt","sequence":"additional","affiliation":[{"name":"Molecular Biology Department, Instituto Valenciano de Oncolog\u00eda (IVO), Valencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 A. 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