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We present a 54-year-old woman with a 10-year recurrence of a conventional chordoma originating from the clivus with lymph node metastasis that was confirmed with brachyury. Based on our review of the literature, there have been only 3 confirmed patients with clival chordoma metastasis to lymph nodes and this is the first account of a conventional chordoma lymph node metastasis being confirmed with brachyury immunohistochemistry.<\/jats:p>","DOI":"10.1177\/10668969251334728","type":"journal-article","created":{"date-parts":[[2025,5,2]],"date-time":"2025-05-02T07:50:55Z","timestamp":1746172255000},"page":"1791-1794","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clival Chordoma Metastatic to Lymph Node: Brachyury Staining Insights"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-7741-5548","authenticated-orcid":false,"given":"Benjamin L.","family":"Petrykowski","sequence":"first","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Conner","family":"Thompson","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tiffany G.","family":"Baker","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cynthia T.","family":"Welsh","sequence":"additional","affiliation":[{"name":"Medical University of South Carolina"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,2]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-020-03511-x"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2018.02.109"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-016-0149-5"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2022.02.037"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-01026-0"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008947301735"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-008-0800-0"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.4103\/0970-9371.112662"},{"issue":"1","key":"e_1_3_2_10_2","first-page":"517657","article-title":"Characteristics and patterns of metastatic disease from chordoma","volume":"2015","author":"Young VA","year":"2015","unstructured":"Young VA, Curtis KM, Temple HT, Eismont FJ, DeLaney TF, Hornicek FJ. Characteristics and patterns of metastatic disease from chordoma. Sarcoma. 2015;2015(1):517657.","journal-title":"Sarcoma"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.906"},{"issue":"5","key":"e_1_3_2_12_2","first-page":"1","article-title":"Sacral chordoma with bilateral inguinal lymph node metastasis and metachronous tumor of the clivus: a case report","volume":"11","author":"Elghareeb MM","year":"2021","unstructured":"Elghareeb MM, Allah MYA, Abdallah SS, Eldesoky AR, Halim AA. Sacral chordoma with bilateral inguinal lymph node metastasis and metachronous tumor of the clivus: a case report. 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Brachyury: a diagnostic marker for the differential diagnosis of chordoma and hemangioblastoma versus neoplastic histological mimickers. Dis Markers. 2014;2014(1):514753.","journal-title":"Dis Markers"},{"key":"e_1_3_2_16_2","volume-title":"Rosai and Ackerman\u2019s surgical pathology","author":"Goldblum JR","year":"2018","unstructured":"Goldblum JR, Lamps LW, McKenney JK, Myers JL, Ackerman LV. Rosai and Ackerman\u2019s surgical pathology. 11th ed. 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