{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T08:29:44Z","timestamp":1787646584081,"version":"build-2736575974"},"reference-count":20,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T00:00:00Z","timestamp":1746489600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2025,12]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The lack of adequate resources in international cooperation limits the study of surgical specimens. The literature on inexpensive and widely available fixation media is scarce.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Materials and Methods<\/jats:title>\n                    <jats:p>Specimens were prospectively collected during a surgical cooperation campaign in Senegal, where a team from Spain provided surgical care to the local population. The lesions were fixed in parallel using 10% formalin and 70% ethyl alcohol. Hematoxylin and eosin (H&amp;E) and immunohistochemical techniques (IHC) were performed. Histological images were independently evaluated by two senior and two junior pathologists through an anonymized questionnaire.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Three surgical specimens were included: 1 lymphoid hyperplasia (3 H&amp;E, 4 IHC), 1 seborrheic keratosis (2 H&amp;E, 5 IHC), and 1 branchial remnant (2 H&amp;E, 2 IHC). Fixation times were similar in all the specimens (10\u201313 days). All formalin H&amp;E were diagnostic. Ethyl alcohol H&amp;E was 100% diagnostic on 5\/7 slides and 75% in the two remaining slides. In most slides, pathologists preferred formalin. Keratin 7, P40, EMA, keratin AE1\/AE3, and TTF1 were 100% diagnostic in both groups. CD20, CD45, and EMA were 100% diagnostic in formalin and 75% diagnostic in ethyl alcohol. CD10 was 75% diagnostic in formalin and 25% diagnostic in ethyl alcohol. BCL6 was 75% diagnostic in formalin and 100% diagnostic in ethyl alcohol. IHC preferences were inconsistent.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Ethyl alcohol shows poorer fixation than formalin but enables diagnosis in most specimens. Immunoreactivity varies by tissue and stain. Further studies are needed to validate these results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10668969251335674","type":"journal-article","created":{"date-parts":[[2025,5,6]],"date-time":"2025-05-06T03:10:14Z","timestamp":1746501014000},"page":"1726-1734","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparison Between 70% Ethyl Alcohol and 10% Formalin as Fixative Mediums in Surgical Cooperation Campaigns: A Pilot Study"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0943-6367","authenticated-orcid":false,"given":"Javier","family":"Arredondo Montero","sequence":"first","affiliation":[{"name":"Pediatric Surgery Department, Complejo Asistencial Universitario de Le\u00f3n, Le\u00f3n, Castilla y Le\u00f3n, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Carracedo Vega","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f3nica","family":"Bronte Anaut","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital General Rio Carri\u00f3n, Palencia, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula","family":"Ortol\u00e1 Fortes","sequence":"additional","affiliation":[{"name":"Pediatric Surgery Department, Hospital Universitario de Castell\u00f3n, Comunidad Valenciana, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yerani","family":"Ruiz de Az\u00faa-Ciria","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adriana","family":"Fern\u00e1ndez-Ariza","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandra","family":"Moreno Ib\u00e9rico","sequence":"additional","affiliation":[{"name":"Complejo Asistencial de \u00c1vila"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yessica Paulina","family":"Rodriguez-Velandia","sequence":"additional","affiliation":[{"name":"Hospital Universitario Donostia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlos","family":"Bardaj\u00ed Pascual","sequence":"additional","affiliation":[{"name":"Independent Scholar"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Guarch Troyas","sequence":"additional","affiliation":[{"name":"Pathology Department, Hospital Universitario de Navarra, Pamplona, Navarra, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,5,6]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.3109\/10520295.2011.590155"},{"issue":"2","key":"e_1_3_3_3_2","first-page":"137","article-title":"Methanol as an alternative fixative for cytological smears","volume":"19","author":"Hemamali RL","year":"1997","unstructured":"Hemamali RL, Kumarasinghe MP, Constantine SR. 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