{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T12:17:54Z","timestamp":1787833074504,"version":"build-2784847793"},"reference-count":20,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T00:00:00Z","timestamp":1765497600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>\n                    Nonsebaceous lymphadenoma-like mucoepidermoid carcinoma (NSLA-like MEC) is an exceedingly rare subtype of MEC. We present such a tumor in a 65-year-old woman with a 2-year history of a left parotid mass. Histologically, the tumor was characterized by a proliferation of neoplastic epithelial cells within a prominent lymphoid stroma containing germinal centers. The epithelial component displayed a bilayered or multitiered growth pattern composed of inner cuboidal cells and outer basaloid cells, forming tubules, microcysts, and complex glandular and cribriform structures. Immunohistochemically, the outer basaloid cells were positive for P63 but were negative for S100 and SMA, while the inner cuboidal cells were positive for keratin 7. Mucicarmine stain demonstrated intracytoplasmic mucin in a small percentage (&lt;1%) of epithelial cells. Fluorescence\n                    <jats:italic toggle=\"yes\">in situ<\/jats:italic>\n                    hybridization analysis revealed\n                    <jats:italic toggle=\"yes\">CRTC1::MAML2<\/jats:italic>\n                    fusion in 78% of tumor cells, confirming the diagnosis of MEC. The morphological distinction between NSLA-like MEC and NSLA poses a significant diagnostic challenge. Features suggestive of MEC include complex branched glandular structures and subtle cytologic atypia. We emphasize the importance of incorporating\n                    <jats:italic toggle=\"yes\">MAML2<\/jats:italic>\n                    molecular testing into diagnostic algorithms for accurate classification, particularly in challenging lesions with lymphoid-rich stroma.\n                  <\/jats:p>","DOI":"10.1177\/10668969251397643","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T16:48:21Z","timestamp":1765558101000},"page":"939-944","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Nonsebaceous Lymphadenoma-like Mucoepidermoid Carcinoma: A Rare Case Report"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-3523-4793","authenticated-orcid":false,"given":"Julin","family":"Liu","sequence":"first","affiliation":[{"name":"Histo Pathology Diagnostic Center, Shanghai, China"},{"name":"CoreOne Pathology Diagnostics Center, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Pathology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiling","family":"Zeng","sequence":"additional","affiliation":[{"name":"Department of Pathology, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yan","family":"Guo","sequence":"additional","affiliation":[{"name":"Histo Pathology Diagnostic Center, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dengfeng","family":"Cao","sequence":"additional","affiliation":[{"name":"Department of Pathology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12105-022-01459-0"},{"key":"e_1_3_2_3_2","volume-title":"WHO Classification of Head and Neck Tumours","author":"Leivo I","year":"2022","unstructured":"Leivo I, Bell D, Katabi N, et al. Mucoepidermoid carcinoma. In: WHO Classification of Head and Neck Tumours. 5th ed. 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