{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:27:02Z","timestamp":1787740022333,"version":"build-2784847793"},"reference-count":32,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T00:00:00Z","timestamp":1773792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:p>\n                    Synovial sarcoma is monomorphic, mostly spindle cell sarcoma, characterized by\n                    <jats:italic toggle=\"yes\">t<\/jats:italic>\n                    (X;18)(p11;q11) translocation, resulting in an\n                    <jats:italic toggle=\"yes\">SS18<\/jats:italic>\n                    ::\n                    <jats:italic toggle=\"yes\">SSX1\/2\/4<\/jats:italic>\n                    fusion gene. It occurs rarely in the gastrointestinal tract. Less than 50 gastric synovial sarcomas have been reported in the literature. We hereby present a 48-year-old male patient, who presented with weight loss and was found to have a mass in his stomach. Histopathological examination of the biopsy revealed a high-grade spindle cell sarcoma in the gastric wall. By immunohistochemistry, the tumor cells were diffusely positive for TLE1 and SS18-SSX, confirming the diagnosis of poorly differentiated synovial sarcoma. The patient underwent surgical resection, followed by adjuvant chemotherapy. He remained disease free for 6 months, following which the disease progressed and he developed metastatic lesions in the liver. Thus, although rare, synovial sarcoma occurs in the stomach and hence it should be included in the list of differential diagnoses of spindle cell sarcomas affecting stomach. A review of literature with treatment implications are discussed herewith.\n                  <\/jats:p>","DOI":"10.1177\/10668969251410251","type":"journal-article","created":{"date-parts":[[2026,3,18]],"date-time":"2026-03-18T13:45:16Z","timestamp":1773841516000},"page":"1225-1234","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Gastric Synovial Sarcoma: A Case Report and Review of Literature"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-8144-6544","authenticated-orcid":false,"given":"Khushi","family":"Naik","sequence":"first","affiliation":[{"name":"Tata Memorial Centre"},{"name":"Homi Bhabha National Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9895-2995","authenticated-orcid":false,"given":"Gauri","family":"Deshpande","sequence":"additional","affiliation":[{"name":"Tata Memorial Centre"},{"name":"Homi Bhabha National Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manish","family":"Bhandare","sequence":"additional","affiliation":[{"name":"Tata Memorial Centre"},{"name":"Homi Bhabha National Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prabhat","family":"Bhargava","sequence":"additional","affiliation":[{"name":"Tata Memorial Centre"},{"name":"Homi Bhabha National Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3509-4794","authenticated-orcid":false,"given":"Bharat","family":"Rekhi","sequence":"additional","affiliation":[{"name":"Tata Memorial Centre"},{"name":"Homi Bhabha National Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mukta","family":"Ramadwar","sequence":"additional","affiliation":[{"name":"Tata Memorial Centre"},{"name":"Homi Bhabha National Institute"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,18]]},"reference":[{"key":"e_1_3_3_2_2","volume-title":"Soft tissue and bone tumours","author":"WHO Classification of Tumours Editorial Board","year":"2020","unstructured":"WHO Classification of Tumours Editorial Board. Soft tissue and bone tumours. International Agency for Research on Cancer; 2020, WHO classification of tumours series, 5th ed., vol. 3."},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20386"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.12809\/hkmj197986"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2020.12.055"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13569-015-0021-3"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.modpat.2023.100383"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.3880011"},{"key":"e_1_3_3_9_2","unstructured":"Akhunji S Musil I de Leon AB Bhattacharyya A. Synovial sarcoma arising in the gastric wall: case report and literature review."},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31812e6a58"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2012.07.010"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/ctg.2012.6"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12328-013-0403-0"},{"issue":"3","key":"e_1_3_3_14_2","first-page":"253","article-title":"Primary gastric synovial sarcoma","volume":"46","author":"Torres Rivas HE","year":"2014","unstructured":"Torres Rivas HE, Fern\u00e1ndez S, Fresno MF. Primary gastric synovial sarcoma. Pathology (Phila). 2014;46(3):253-256.","journal-title":"Pathology (Phila)"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-014-9591-1"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/his.12593"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12029-017-9979-9"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000008904"},{"key":"e_1_3_3_19_2","unstructured":"Olsen G. Primary gastric synovial sarcoma mimicking a gastrointestinal stromal tumor (GIST)."},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-018-4065-6"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i8.949"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.14309\/01.ajg.0000597232.39299.ec"},{"issue":"1","key":"e_1_3_3_23_2","article-title":"Primary gastric synovial sarcoma in a child: a case report and review of the literature","volume":"43","author":"Manohar A","year":"2021","unstructured":"Manohar A, Gopal C, Premalata C, et al. Primary gastric synovial sarcoma in a child: a case report and review of the literature. J PediatrHematol Oncol. 2021;43(1):e119-e122.","journal-title":"J PediatrHematol Oncol"},{"issue":"1","key":"e_1_3_3_24_2","first-page":"115","article-title":"A minute primary gastric synovial sarcoma with ulcer: a case report","volume":"16","author":"Yoshiyasu K","year":"2021","unstructured":"Yoshiyasu K, Kono H, Hojo Y, et al. A minute primary gastric synovial sarcoma with ulcer: a case report. DiagnPathol. 2021;16(1):115.","journal-title":"DiagnPathol"},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40792-021-01310-8"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.24407"},{"issue":"5","key":"e_1_3_3_27_2","first-page":"766","article-title":"Immunohistochemical validation of TLE1, a novel marker, for synovial sarcomas","volume":"136","author":"Rekhi B","year":"2012","unstructured":"Rekhi B, Basak R, Desai SB, Jambhekar NA. Immunohistochemical validation of TLE1, a novel marker, for synovial sarcomas. 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