{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T12:17:54Z","timestamp":1787833074670,"version":"build-2784847793"},"reference-count":18,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T00:00:00Z","timestamp":1769126400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2026,6]]},"abstract":"<jats:p>Chronic silicone embolism represents a rare complication associated with silicone breast implants. With the increasing number of breast augmentations and reconstructive surgeries performed worldwide, awareness of implant-related pulmonary pathology is becoming increasingly important. This issue gained more public attention after the Poly Implant Proth\u00e8se scandal, which involved the use of cheaper industrial-grade silicone with a significantly higher risk of implant rupture. Here, we present a 54-year-old woman with a history of bilateral implant rupture, to highlight implant-related complications, specifically silicone migration into the lungs and other parts of the body. Ten years later, the patient experienced occasional episodes of shortness of breath for approximately 1 year, and imaging revealed multiple pulmonary lesions. Silicone particles triggered a florid chronic inflammatory reaction in the pulmonary parenchyma, rich in T-lymphocytes, histologically mimicking hematologic malignancy. Explantation of the breast implants was performed, and over the following 3 years, the patient's symptoms spontaneously subsided.<\/jats:p>","DOI":"10.1177\/10668969251410616","type":"journal-article","created":{"date-parts":[[2026,1,23]],"date-time":"2026-01-23T12:51:42Z","timestamp":1769172702000},"page":"1058-1063","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Chronic Silicone Embolism Syndrome"],"prefix":"10.1177","volume":"34","author":[{"given":"Tereza","family":"Sokolova","sequence":"first","affiliation":[{"name":", Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove and Charles University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jakub","family":"Sagat","sequence":"additional","affiliation":[{"name":", Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove and Charles University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucia","family":"Hrnciarova","sequence":"additional","affiliation":[{"name":", Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove and Charles University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6129-9841","authenticated-orcid":false,"given":"Vaclav","family":"Stejskal","sequence":"additional","affiliation":[{"name":", Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove and Charles University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,23]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0042-1756204"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.carpath.2017.06.004"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.127.6.2276"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198303313081307"},{"issue":"4","key":"e_1_3_2_6_2","first-page":"380","article-title":"Case report and literature review: Acute pneumonitis and alveolar hemorrhage after subcutaneous injection of liquid silicone","volume":"38","author":"Parikh R","year":"2008","unstructured":"Parikh R, Karim K, Parikh N, Han P, Daoko J, Shamoon FE. Case report and literature review: Acute pneumonitis and alveolar hemorrhage after subcutaneous injection of liquid silicone. Ann Clin Lab Sci. 2008;38(4):380\u2010385.","journal-title":"Ann Clin Lab Sci"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3349\/ymj.2002.43.2.152"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.resmer.2023.101065"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/his.12518"},{"key":"e_1_3_2_10_2","unstructured":"European Commission. Directorate General for Health and Food Safety. Scientific advice on evaluation of the availability of new scientific information on the safety of PIP breast implants. Publications Office; 2017. Accessed September 8 2025. https:\/\/data.europa.eu\/doi\/10.2875\/058745"},{"issue":"7","key":"e_1_3_2_11_2","first-page":"371","article-title":"Migration of silicone gel to axillary lymph nodes after prosthetic mammoplasty","volume":"105","author":"Hausner RJ","year":"1981","unstructured":"Hausner RJ, Schoen FJ, Mendez-Fernandez MA, Henly WS, Geis RC. Migration of silicone gel to axillary lymph nodes after prosthetic mammoplasty. 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