{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T10:27:20Z","timestamp":1787740040894,"version":"build-2784847793"},"reference-count":17,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,3,9]],"date-time":"2026-03-09T00:00:00Z","timestamp":1773014400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"the Japan Society for the Promotion of Science (JSPS) KAKENHI","award":["25K20153"],"award-info":[{"award-number":["25K20153"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:p>\n                    <jats:italic toggle=\"yes\">FUS<\/jats:italic>\n                    ::\n                    <jats:italic toggle=\"yes\">TFCP2<\/jats:italic>\n                    -positive rhabdomyosarcoma (RMS) is a rare and aggressive subtype that was recently classified as a distinct entity. It is resistant to conventional chemotherapeutic regimens for RMS, and optimal treatment strategies have not been established. Here, we describe an 11-year-old boy with mandibular RMS with a\n                    <jats:italic toggle=\"yes\">FUS<\/jats:italic>\n                    ::\n                    <jats:italic toggle=\"yes\">TFCP2<\/jats:italic>\n                    fusion gene. At the referring hospital, the patient initially underwent standard induction chemotherapy for RMS, but it was ineffective. Radical resection, including segmental mandibulectomy and reconstruction with a rectus abdominis free flap, was performed. Histological examination of the surgical specimen revealed a viable tumor with minimal response to chemotherapy. The patient had remained disease-free for 18 months. Our experience highlights that early pathological diagnosis and prompt surgical intervention for\n                    <jats:italic toggle=\"yes\">FUS<\/jats:italic>\n                    ::\n                    <jats:italic toggle=\"yes\">TFCP2<\/jats:italic>\n                    fusion-positive RMS are crucial due to its chemoresistance.\n                  <\/jats:p>","DOI":"10.1177\/10668969251414872","type":"journal-article","created":{"date-parts":[[2026,3,11]],"date-time":"2026-03-11T10:27:32Z","timestamp":1773224852000},"page":"1247-1255","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Successful Surgical Treatment of Pediatric\n                    <i>FUS<\/i>\n                    ::\n                    <i>TFCP2<\/i>\n                    -Positive Rhabdomyosarcoma of the Mandible: A Case Report"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0922-9245","authenticated-orcid":false,"given":"Kohtaro","family":"Eguchi","sequence":"first","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eriko","family":"Uchida","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0771-3551","authenticated-orcid":false,"given":"Koichi","family":"Oshima","sequence":"additional","affiliation":[{"name":"Saitama Children's Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kohei","family":"Fukuoka","sequence":"additional","affiliation":[{"name":"Saitama Children's Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8147-9935","authenticated-orcid":false,"given":"Kayoko","family":"Tao","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayumu","family":"Arakawa","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chihiro","family":"Fushimi","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Go","family":"Omura","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Taisuke","family":"Mori","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akihiko","family":"Yoshida","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katsuyoshi","family":"Koh","sequence":"additional","affiliation":[{"name":"Saitama Children's Medical Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9270-095X","authenticated-orcid":false,"given":"Seiichi","family":"Yoshimoto","sequence":"additional","affiliation":[{"name":"National Cancer Center Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,9]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.sempedsurg.2016.09.011"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00432-017-2544-x"},{"key":"e_1_3_2_4_2","volume-title":"Head and neck tumours","author":"WHO Classification of Tumours Editorial Board","year":"2022","unstructured":"WHO Classification of Tumours Editorial Board. 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