{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T15:07:08Z","timestamp":1788880028447,"version":"build-2803163510"},"reference-count":7,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T00:00:00Z","timestamp":1777852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"published-print":{"date-parts":[[2026,10]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>\n                      NUT carcinoma (NC) is a rare, aggressive squamous-lineage malignancy characterized by\n                      <jats:italic toggle=\"yes\">NUTM1<\/jats:italic>\n                      gene rearrangement and distinctive nuclear NUT expression by immunohistochemistry. Ocular adnexal involvement is exceptional.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patient presentation<\/jats:title>\n                    <jats:p>\n                      A 26-year-old woman presented with redness, pruritus, and a large nasal canthal mass obstructing vision in the left eye. Examination showed a 4\u2009\u00d7\u20093\u2005cm lacrimal mass extending into the extraconal orbit with extraocular muscle compression. Histology showed nests of small round blue cells with crush artifact and abrupt keratinization. Immunohistochemistry demonstrated diffuse pan-keratin, p63, p40, and speckled nuclear\n                      <jats:italic toggle=\"yes\">NUTM1<\/jats:italic>\n                      positivity; CD99 and NKX2.2 were negative\u2014confirming NC.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Lacrimal sac\/gland NC should be considered in rapidly enlarging medial canthal masses in young patients. Prompt biopsy with IMMUNOHISTOCHEMISTRY for NUT and early multidisciplinary management are critical.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10668969261439157","type":"journal-article","created":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T15:27:18Z","timestamp":1777908438000},"page":"1849-1852","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["NUT Carcinoma of the Lacrimal Apparatus Presenting as a Rapidly Enlarging Medial Canthal Mass: A Case Report"],"prefix":"10.1177","volume":"34","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7807-4788","authenticated-orcid":false,"given":"Pratiksha Vidhe","family":"Sharma","sequence":"first","affiliation":[{"name":"Symbiosis Medical College for Women & Symbiosis University Hospital & Research Centre, Symbiosis International (Deemed University)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8894-1555","authenticated-orcid":false,"given":"Harshala H.","family":"Lokhande","sequence":"additional","affiliation":[{"name":"Symbiosis Medical College for Women & Symbiosis University Hospital & Research Centre, Symbiosis International (Deemed University)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4800-5954","authenticated-orcid":false,"given":"Shruti","family":"Vimal","sequence":"additional","affiliation":[{"name":"Symbiosis Medical College for Women & Symbiosis University Hospital & Research Centre, Symbiosis International (Deemed University)"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,5,4]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/pin.12727"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S173056"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.26067"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13000-019-0922-1"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000001967"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.21037\/tcr-22-364"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2023.1098704"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969261439157","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10668969261439157","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969261439157","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,8]],"date-time":"2026-09-08T14:17:36Z","timestamp":1788877056000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10668969261439157"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,4]]},"references-count":7,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026,10]]}},"alternative-id":["10.1177\/10668969261439157"],"URL":"https:\/\/doi.org\/10.1177\/10668969261439157","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,4]]}}}