{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T08:24:29Z","timestamp":1787300669812,"version":"build-2736575974"},"reference-count":14,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T00:00:00Z","timestamp":1786924800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Cooperatio","award":["SURG"],"award-info":[{"award-number":["SURG"]}]},{"name":"Ministry of Health of the Czech Republic -Conceptual Development of Research Organization (Faculty Hospital in Pilsen -FNPl","award":["00669806"],"award-info":[{"award-number":["00669806"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"abstract":"<jats:p>\n                    Adenoid cystic\/basal cell carcinoma (ACBCC) of the prostate is a rare tumor, with only about 100 tumors reported in the literature. We present a 66-year-old man with incidental finding of prostatic cancer duplicity\u2014ACBCC of the prostate and prostatic acinar adenocarcinoma in radical prostatectomy specimen. Prostatic acinar adenocarcinoma was of Gleason score 6 (3\u2009+\u20093), focally present at surgical margin, exhibited perineural invasion but no extraprostatic extension. Concurrently, ACBCC was detected, the tumor exhibited adenoid cystic-like morphology, with multifocal involvement of the resection margins and extraprostatic extension. This coincidence presented a unique opportunity to comprehensively examine the molecular characteristics of both tumors.\n                    <jats:italic toggle=\"yes\">SETD2<\/jats:italic>\n                    mutation was identified in ACBCC, while it was absent in acinar adenocarcinoma. No significant differences were detected by other genetic analyses, and both tumors clustered together within \u201cProstatic adenocarcinoma\u201d control group and separated from adenoid cystic carcinoma of other locations using methylation profiling.\n                  <\/jats:p>","DOI":"10.1177\/10668969261464473","type":"journal-article","created":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T13:50:53Z","timestamp":1786974653000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Concurrent Adenoid Cystic\/Basal Cell Carcinoma and Acinar Adenocarcinoma of the Prostate: Comprehensive Molecular Analysis of Both Tumor Component"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9553-0105","authenticated-orcid":false,"given":"Kristyna","family":"Pivovarcikova","sequence":"first","affiliation":[{"name":"\u0160ikl's Department of Pathology, Faculty of Medicine and University 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