{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,27]],"date-time":"2026-09-27T14:57:48Z","timestamp":1790521068352,"version":"4.1.0"},"reference-count":31,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:00:00Z","timestamp":1790208000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"abstract":"<jats:p>Mammary myofibroblastoma (MFB) is a rare benign mesenchymal tumor of the breast with myofibroblastic differentiation. Its diverse morphological spectrum may pose diagnostic challenges, particularly in limited biopsy specimens. All MFB patients diagnosed at a tertiary care center between 2015 and 2024 were reviewed retrospectively. Eleven patients were identified, including 7 women and 4 men, with a mean age of 56.5 years (range: 31-75 years). All patients presented with a solitary, painless breast mass. Tumor size ranged from 2.3 to 14\u2005cm. Histologically, 9 tumors showed spindle cell morphology, whereas 2 showed epithelioid features. The common findings included short intersecting fascicles of bland spindle cells, variable collagen deposition, ectatic blood vessels, and focal adipocytic components. Immunohistochemically, CD34 was positive in 9 tumors, desmin in 8, smooth muscle actin (ACTA2) in 5, BCL2 and CD99 in 7 each, and CD10 in 4 tumors. Keratin AE1\/AE3, p63, S100, and STAT6 were negative in all tumors. Follow-up data was available in 9 patients and no recurrence was reported. Recognition of its characteristic morphological and immunohistochemical features is essential to avoid diagnostic pitfalls. Complete surgical excision is curative, with an excellent prognosis.<\/jats:p>","DOI":"10.1177\/10668969261469873","type":"journal-article","created":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T08:26:28Z","timestamp":1790238388000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Clinicopathological Features of Mammary Myofibroblastoma: A Single Institution Case Series"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2548-2427","authenticated-orcid":false,"given":"Hania","family":"Naveed","sequence":"first","affiliation":[{"name":"Aga Khan University, Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6980-0231","authenticated-orcid":false,"given":"Romana","family":"Idrees","sequence":"additional","affiliation":[{"name":"Aga Khan University, Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-4157-9542","authenticated-orcid":false,"given":"Fatima","family":"Safdar","sequence":"additional","affiliation":[{"name":"Aga Khan University, Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1036-5121","authenticated-orcid":false,"given":"Nasir Ud","family":"Din","sequence":"additional","affiliation":[{"name":"Aga Khan University, Hospital"},{"name":"Department of Pathology and Laboratory Medicine, University of Miami, Miller School of Medicine, Miami, FL, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5306-4257","authenticated-orcid":false,"given":"Naila","family":"Kayani","sequence":"additional","affiliation":[{"name":"Aga Khan University, Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,24]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3233\/BD-150403"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.5858\/2008-132-1813-MMATWW"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjab132"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.7759\/cureus"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198707000-00001."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200108000-00006"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1177\/10668969231168147"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.30699\/ijp.2021.130301.2642"},{"issue":"1","key":"e_1_3_2_10_2","first-page":"1","article-title":"Myofibroblastoma of the breast: Literature review and case report","volume":"2016","author":"Metry M","year":"2016","unstructured":"Metry M, Shaaban M, Youssef M, et al. 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