{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T14:02:24Z","timestamp":1789912944914,"version":"4.0.1"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T00:00:00Z","timestamp":1789689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Int J Surg Pathol"],"abstract":"<jats:p>\n                    An 81-year-old man with a history of multiple skin cancers presented with a change to a longstanding lesion. Biopsy confirmed microcystic adnexal carcinoma. The lesion was excised with clear margins. Over the course of 5 years, the tumor recurred four times in the periorbital and orbital area. Histopathology showed progressively poorer differentiation, with increasing mitotic activity and decreasing ductular differentiation. Next-generation sequencing testing demonstrated a Tier III variant of unknown significance in\n                    <jats:italic toggle=\"yes\">ARID1A<\/jats:italic>\n                    and was otherwise negative for gene mutations and fusions in a panel of 141 cancer-related genes. Orbital invasion necessitated exenteration 5 years after initial presentation and adjuvant radiation was used to decrease the risk of recurrence. The patient subsequently experienced metastasis to the parotid and regional lymph nodes. Seven and a half years after initial presentation, the patient is clear of disease and on regular follow-up.\n                  <\/jats:p>","DOI":"10.1177\/10668969261479349","type":"journal-article","created":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T13:44:47Z","timestamp":1789739087000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Ocular Microcystic Adnexal Carcinoma With High-Grade Features: A Case Report With Orbital Exenteration"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4740-9789","authenticated-orcid":false,"given":"Katherina","family":"Baranova","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Corey","family":"Moore","sequence":"additional","affiliation":[{"name":"Western University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adam","family":"Mutsaers","sequence":"additional","affiliation":[{"name":"Western University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7224-5216","authenticated-orcid":false,"given":"Matthew","family":"Cecchini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4928-2742","authenticated-orcid":false,"given":"Qi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Western University"},{"name":"Western University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3152-3480","authenticated-orcid":false,"given":"David JA","family":"Plemel","sequence":"additional","affiliation":[{"name":"Western University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,18]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19820801)50:3%3C566::aid-cncr2820500330%3E3.0.co;2-q"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2009.374"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000034709"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000002167"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0b013e31819791eb"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1159\/000090575"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.IOP.0000155508.52870.DA"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamadermatol.2019.1251"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41379-019-0424-4"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000001142"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1111\/his.14130"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2004.30271.x"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000372-200608000-00011"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-199809030-00014"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4725.2007.33069.x"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1080\/01676830.2018.1440607"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/IOP.0000000000000869"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21690"}],"container-title":["International Journal of Surgical Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969261479349","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10668969261479349","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10668969261479349","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T13:47:53Z","timestamp":1789912073000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10668969261479349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,18]]},"references-count":18,"alternative-id":["10.1177\/10668969261479349"],"URL":"https:\/\/doi.org\/10.1177\/10668969261479349","relation":{},"ISSN":["1066-8969","1940-2465"],"issn-type":[{"value":"1066-8969","type":"print"},{"value":"1940-2465","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,18]]},"article-number":"10668969261479349"}}