{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,21]],"date-time":"2025-10-21T15:11:12Z","timestamp":1761059472837,"version":"3.38.0"},"reference-count":16,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T00:00:00Z","timestamp":1359676800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foot Ankle Int."],"published-print":{"date-parts":[[2013,2]]},"abstract":"<jats:sec><jats:title>Background:<\/jats:title><jats:p> Patients with Charcot arthropathy present a high risk for ulcers with secondary bone infection. Infections with Pseudomonas aeruginosa represent a severe threat to the patients. We hypothesized that infections with P aeruginosa result in a longer stay in hospital and more operations than infections with other bacteria. <\/jats:p><\/jats:sec><jats:sec><jats:title>Methods:<\/jats:title><jats:p> All patients who underwent surgery for Charcot arthropathy of the feet between 1996 and 2006 (n = 205) in our clinic were included. The duration of hospitalization and number of surgeries for infections due to methicillin-resistant Staphylococcus aureus (MRSA) versus P aeruginosa were compared to infections with other bacteria. All patients were scanned for MRSA and were isolated when tested positive and treated according to a defined algorithm. <\/jats:p><\/jats:sec><jats:sec><jats:title>Results:<\/jats:title><jats:p> Seventy-nine intraoperative samples exhibited bacterial growth: 12 cases of MRSA, 14 cases of P aeruginosa, and 53 case of other bacteria. Patients with deep infections due to P aeruginosa stayed significantly longer in the hospital (52 vs 35 days, P &lt; .041) and needed significantly more surgery (1.71 vs 1.28 surgeries, P &lt; .027). There was no significant difference between patients with MRSA infections and those without MRSA or P aeruginosa. <\/jats:p><\/jats:sec><jats:sec><jats:title>Conclusion:<\/jats:title><jats:p> Infections with P aeruginosa resulted in more surgeries and a longer stay in the hospital. Early debridement is the basic treatment. A specific algorithm for isolation and operative and antibiotic treatment for P aeruginosa infections is proposed similar to an algorithm for MRSA that has been shown to be successful. <\/jats:p><\/jats:sec><jats:sec><jats:title>Level of Evidence:<\/jats:title><jats:p> Level IV, retrospective case Series. <\/jats:p><\/jats:sec>","DOI":"10.1177\/1071100712464212","type":"journal-article","created":{"date-parts":[[2013,2,14]],"date-time":"2013-02-14T19:41:50Z","timestamp":1360870910000},"page":"234-237","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Infections With Pseudomonas Aeruginosa in Charcot Arthropathy of the Foot"],"prefix":"10.1177","volume":"34","author":[{"given":"Ulrich","family":"Illgner","sequence":"first","affiliation":[{"name":"Universit\u00e4tsklinikum M\u00fcnster, Muenster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Uekoetter","sequence":"additional","affiliation":[{"name":"Institute of Medical Microbiology, University Hospital Muenster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Runge","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum M\u00fcnster, Muenster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans Henning","family":"Wetz","sequence":"additional","affiliation":[{"name":"Universit\u00e4tsklinikum M\u00fcnster, Muenster, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,2,14]]},"reference":[{"key":"bibr1-1071100712464212","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.77a.09163"},{"key":"bibr2-1071100712464212","unstructured":"Bowker JH. 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Accessed January 24, 2011."},{"key":"bibr7-1071100712464212","first-page":"227","volume-title":"Levin and O\u2019Neal\u2019s the Diabetic Foot","volume":"2007","author":"Hoppe H","edition":"7"},{"key":"bibr8-1071100712464212","doi-asserted-by":"publisher","DOI":"10.1007\/s00132-006-1015-x"},{"key":"bibr9-1071100712464212","doi-asserted-by":"publisher","DOI":"10.1007\/s00132-009-1504-9"},{"key":"bibr10-1071100712464212","doi-asserted-by":"publisher","DOI":"10.1007\/s00132-009-1507-6"},{"key":"bibr11-1071100712464212","doi-asserted-by":"publisher","DOI":"10.1007\/s00392-006-0328-4"},{"key":"bibr12-1071100712464212","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(04)16727-5"},{"key":"bibr13-1071100712464212","first-page":"305","volume-title":"Levin and O\u2019Neal\u2019s the Diabetic Foot","volume":"2007","author":"Lipsky BA","edition":"7"},{"key":"bibr14-1071100712464212","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(01)00094-9"},{"key":"bibr15-1071100712464212","first-page":"2701","volume":"95","author":"Wetz HH","year":"1998","journal-title":"Dtsch \u00c4rztebl A"},{"key":"bibr16-1071100712464212","unstructured":"World Health Organization. http:\/\/www.who.int\/dietphysicalactivity\/publications\/facts\/diabetes\/en\/. 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