{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:16:11Z","timestamp":1777612571196,"version":"3.51.4"},"reference-count":29,"publisher":"SAGE Publications","issue":"10","license":[{"start":{"date-parts":[[2013,4,25]],"date-time":"2013-04-25T00:00:00Z","timestamp":1366848000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Foot Ankle Int."],"published-print":{"date-parts":[[2013,10]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The purpose of this study was to evaluate the clinical outcomes and usefulness of OK-432 (Picibanil) sclerotherapy as a new option in the conservative treatment of patients with malleolar bursitis of the ankle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Retrospectively, we reviewed a total of 20 consecutive patients (20 feet) in whom OK-432 sclerotherapy had been performed between March 2009 and June 2010. After aspiration of fluid in the malleolar bursal sac, 0.05 mg of OK-432 was injected into the malleolar bursal sac. We evaluated the clinical outcomes and side effects at the following time points: 2 weeks, 1 month, 3 months, 6 months, and 1 year after OK-432 sclerotherapy. The responses to the treatment were assessed according to the degree of fluctuation, shrinkage of the bursal sac, and soft tissue swelling.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Complete resolution was observed in 19 patients (95%) after the first or second application of OK-432 sclerotherapy, and a partial response was observed in 1 patient (5%) after a second application of OK-432 sclerotherapy. The physical component scores of SF-36 improved from 70.0 \u00b1 6.8 to 76.5 \u00b1 7.3 at the last follow-up ( P = .0002).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>OK-432 sclerotherapy was a useful procedure for patients not responding to the usual conservative treatment of malleolar bursitis of the ankle.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Level of Evidence:<\/jats:title>\n                    <jats:p>Level IV, retrospective case series.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1071100713488091","type":"journal-article","created":{"date-parts":[[2013,4,25]],"date-time":"2013-04-25T23:53:58Z","timestamp":1366934038000},"page":"1389-1394","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["OK-432 Sclerotherapy for Malleolar Bursitis of the Ankle"],"prefix":"10.1177","volume":"34","author":[{"given":"Kwang Hwan","family":"Park","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, Korea"},{"name":"Department of Microbiology, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jongseok","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, KEPCO Medical Center, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Woo Jin","family":"Choi","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin Woo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Yonsei University College of Medicine, Seoul, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,4,25]]},"reference":[{"key":"bibr1-1071100713488091","doi-asserted-by":"publisher","DOI":"10.1177\/107110070102200112"},{"key":"bibr2-1071100713488091","unstructured":"Boutin FJ, Boutin RD, Boutin FJJr. In: Bursitis. 2nd ed. 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Picibanil INJ 5KE [in Korean]. http:\/\/www.kimsonline.co.kr\/091_DrugInfo\/DrugBasicInfo.aspx?KIMSCode=ECGISIJ01XD. 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