{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:51:28Z","timestamp":1777611088117,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[1982,1,1]],"date-time":"1982-01-01T00:00:00Z","timestamp":378691200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Foot &amp; Ankle"],"published-print":{"date-parts":[[1982,1]]},"abstract":"<jats:p>Basic genetic principles are reviewed, with special reference to foot anomalies. The cytogenetics of Mendelian disorders (autosomal dominant, autosomal recessive, X-linked dominant, and X-linked recessive) are explained, with attention to penetrance and variable expressivity. Multifactorial conditions and chromosome structural defects are also discussed. The value of tracing family genetic patterns and performing chromosome studies for diagnosing and counseling orthopaedic patients is underscored. The mechanics of genetic principles, explained in the article, are shown to be worthwhile tools in orthopaedic medicine.<\/jats:p>","DOI":"10.1177\/107110078200200403","type":"journal-article","created":{"date-parts":[[2013,3,3]],"date-time":"2013-03-03T03:24:58Z","timestamp":1362281098000},"page":"185-189","source":"Crossref","is-referenced-by-count":1,"title":["Genetic Considerations of Foot Anomalies in Office Practice"],"prefix":"10.1177","volume":"2","author":[{"given":"Barry K.","family":"Wein","sequence":"first","affiliation":[{"name":"Alfred I. duPont Institute, Wilmington, Delaware"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry R.","family":"Cowell","sequence":"additional","affiliation":[{"name":"Alfred I. duPont Institute, Wilmington, Delaware"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1982,1,1]]},"reference":[{"key":"bibr1-107110078200200403","first-page":"55","volume":"7","author":"Cowell H.R.","year":"1978","journal-title":"Orthop. 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Bone Joint Surg."},{"key":"bibr8-107110078200200403","doi-asserted-by":"crossref","first-page":"1436","DOI":"10.2106\/00004623-196749070-00021","volume":"49","author":"Nance W.E.","year":"1967","journal-title":"J. Bone Joint Surg."},{"key":"bibr9-107110078200200403","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/S0030-5898(20)31244-X","volume":"5","author":"Palmer R.M.","year":"1974","journal-title":"Orthop. Clin. North Am."},{"key":"bibr10-107110078200200403","volume-title":"The Chromosome Disorders: An Introduction for Clinicians.","author":"Valentine G.H.","year":"1975","edition":"3"},{"key":"bibr11-107110078200200403","volume-title":"Human Chromosome Methodology.","author":"Yunis J.J.","year":"1974","edition":"2"}],"container-title":["Foot &amp; Ankle"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/107110078200200403","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/107110078200200403","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/107110078200200403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T21:18:42Z","timestamp":1777411122000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/107110078200200403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1982,1]]},"references-count":11,"journal-issue":{"issue":"4","published-print":{"date-parts":[[1982,1]]}},"alternative-id":["10.1177\/107110078200200403"],"URL":"https:\/\/doi.org\/10.1177\/107110078200200403","relation":{},"ISSN":["0198-0211"],"issn-type":[{"value":"0198-0211","type":"print"}],"subject":[],"published":{"date-parts":[[1982,1]]}}}