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Exploratory structural equation modeling (ESEM) was used to show that a five-factor solution provided acceptable model fit, albeit with some poorly functioning items. Neuroticism demonstrated significant positive associations with all but one of the disorder constructs whereas Extraversion was inversely related to SOC and MDD. Conscientiousness was inversely related to MDD but demonstrated a positive relationship with GAD. Results are discussed in regard to potential revisions to the NEO FFI, the evaluation of other NEO instruments using ESEM, and clinical implications of structural paths between FFM domains and specific emotional disorders.<\/jats:p>","DOI":"10.1177\/1073191110382848","type":"journal-article","created":{"date-parts":[[2010,9,29]],"date-time":"2010-09-29T23:13:54Z","timestamp":1285802034000},"page":"27-38","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":159,"title":["The NEO Five-Factor Inventory: Latent Structure and Relationships With Dimensions of Anxiety and Depressive Disorders in a Large Clinical Sample"],"prefix":"10.1177","volume":"18","author":[{"given":"Anthony J.","family":"Rosellini","sequence":"first","affiliation":[{"name":"Boston University, Boston, MA, USA,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy A.","family":"Brown","sequence":"additional","affiliation":[{"name":"Boston University, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,9,29]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1016\/j.paid.2004.11.014"},{"key":"atypb2","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association.","year":"1987","edition":"3"},{"key":"atypb3","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association.","year":"2000","edition":"4"},{"key":"atypb4","volume-title":"Reformulation of personality disorders in DSM-V","author":"American Psychiatric Association.","year":"2010"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1023\/A:1021836830389"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1002\/da.20658"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1080\/10705510903008204"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/S0191-8869(99)00055-0"},{"key":"atypb9","doi-asserted-by":"publisher","DOI":"10.1177\/070674370805300605"},{"key":"atypb10","volume-title":"Anxiety and its disorders: The nature and treatment of anxiety and panic","author":"Barlow, D.H.","year":"2002","edition":"2"},{"key":"atypb11","doi-asserted-by":"publisher","DOI":"10.1207\/s15328007sem1201_3"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-1781(01)00228-1"},{"key":"atypb13","doi-asserted-by":"publisher","DOI":"10.1002\/da.20026"},{"key":"atypb14","volume-title":"Confirmatory factor analysis for applied research","author":"Brown, T.A.","year":"2006"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.116.2.313"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.114.4.551"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1037\/a0016608"},{"key":"atypb18","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.107.2.179"},{"key":"atypb19","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.110.4.585"},{"key":"atypb20","doi-asserted-by":"publisher","DOI":"10.1037\/0021-843X.110.1.49"},{"key":"atypb21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0447.2006.00826.x"},{"key":"atypb22","volume-title":"The descriptions and measurement of personality","author":"Cattell, R.B.","year":"1946"},{"key":"atypb23","doi-asserted-by":"publisher","DOI":"10.1037\/0022-3514.66.1.93"},{"key":"atypb24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2005.06.010"},{"key":"atypb25","volume-title":"The NEO-PI\/NEO-FFI manual supplement","author":"Costa, P.T.","year":"1989"},{"key":"atypb26","volume-title":"NEO PI-R professional manual: Revised NEO Personality Inventory (NEO PI-R) and NEO Five-Factor Inventory (NEO-FFI)","author":"Costa, P.T.","year":"1992"},{"key":"atypb27","doi-asserted-by":"publisher","DOI":"10.1037\/10423-000"},{"key":"atypb28","volume-title":"Anxiety disorders interview schedule for DSM-IV: Lifetime version (ADIS-IV-L)","author":"Di Nardo, P.A.","year":"1994"},{"key":"atypb29","doi-asserted-by":"publisher","DOI":"10.1016\/S0005-7967(97)00070-3"},{"key":"atypb30","doi-asserted-by":"publisher","DOI":"10.1016\/S0191-8869(99)00242-1"},{"key":"atypb31","doi-asserted-by":"publisher","DOI":"10.1016\/0191-8869(94)90291-7"},{"key":"atypb32","doi-asserted-by":"publisher","DOI":"10.1080\/10705519909540118"},{"key":"atypb33","doi-asserted-by":"publisher","DOI":"10.1037\/0021-9010.87.4.797"},{"key":"atypb34","doi-asserted-by":"publisher","DOI":"10.1017\/S0033291709991140"},{"key":"atypb35","unstructured":"Marsh, H.W., Hau, K.T. & Grayson, D. 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