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The preliminary evaluation of the item\u2019s importance of the original CHBQOL and the final review of the short form of CHBQOL (CHBQOL-SF) were collected by the Delphi method. A bi-factor model was estimated and Rasch analysis with partial credit model was performed on each domain of the CHBQOL. Six items were suggested to remove based on the Delphi results. The fit of the bi-factor model was acceptable (RMSEA = 0.040; CFI = 0.983; TLI = 0.965). Disordered thresholds were initially found on three out of five items in Somatic symptoms, and four out of six items in Social stigma. Uniform differential item functioning was observed for three items for age group, two items for gender, and one item each for different ALT levels and HBV-DNA levels. Finally, the 10-item CHBQOL-SF retained the four-dimensional structure of the original instrument. The 10 items fit the Rasch model well and response options were set reasonably. The 10-item CHBQOL-SF would offer a brief and easily administrative CHB-specific patient-reported outcome measure for use in clinical practice and population studies.<\/jats:p>","DOI":"10.1177\/10731911251321922","type":"journal-article","created":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T01:35:15Z","timestamp":1742434515000},"page":"303-319","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Development of the Short Form for Chronic Hepatitis B Quality of Life Instrument (CHBQOL-SF) Using Delphi Method and Rasch Analysis"],"prefix":"10.1177","volume":"33","author":[{"given":"Renjun","family":"Gu","sequence":"first","affiliation":[{"name":"Department of Social Medicine, School of Public Health and Department of Pharmacy, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lin","family":"Zhu","sequence":"additional","affiliation":[{"name":"Shanghai Health Development Research Center (Shanghai Medical Information Center), Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingxia","family":"Kong","sequence":"additional","affiliation":[{"name":"Shulan International Medical College of Zhejiang Shuren University, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Social Medicine, School of Public Health and Department of Pharmacy, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mengna","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Social Medicine, School of Public Health and Department of Pharmacy, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Medical Administration, Tianjin Children\u2019s Hospital, Tianjin, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald L.","family":"Patrick","sequence":"additional","affiliation":[{"name":"Department of Health Systems and Population Health, University of Washington, Seattle, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7565-9040","authenticated-orcid":false,"given":"Hongmei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Social Medicine, School of Public Health and Department of Pharmacy, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,3,19]]},"reference":[{"key":"e_1_3_3_2_1","doi-asserted-by":"crossref","unstructured":"Amin L. 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