{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:29:48Z","timestamp":1777483788060,"version":"3.51.4"},"reference-count":47,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2019,1,1]]},"abstract":"<jats:p>Multiple myeloma (MM) is characterized by bone pain, pathologic fractures, bone destruction, and secondary hypercalcemia, all these conditions impact on health-related quality of life of patients. The objective was to evaluate the global health state and health-related quality of life in a group of patients with MM who attended a tertiary health-care center of the Instituto Mexicano del Seguro Social in Mexico, through the questionnaires designed by European Organization for Research and Treatment of Cancer (EORTC) quality of life group. Exploratory cross-sectional study in patients with MM treated in a Department of Hematology in a High-Specialty Medical Unit was conducted. Patients older than 18 years of age, men and women, were selected, and their informed written consent was obtained. We included all consecutive cases treated from January 2012 to December 2014. Questionnaires EORTC QLQ-C30, EORTC QLQ-MY20, and EORTC IN-PATSAT-32 were used. We studied 37 patients, 19 (51%) men and 18 women. The mean age was 61.9 years. Twenty-two (59.46%) patients presented with clinical stage III. The mean time for diagnosis was 33.11 months. The most used first-line treatment schedule was melphalan\/prednisone\/thalidomide (15; 40%). The global health median was 66.67, and symptoms showed a median score of 22.22. Treatment side effects score was 16.67; for general satisfaction, the median score was 75. In conclusion, the patients showed an advanced clinical stage and poor prognosis but had scores higher than 50 in functional scales and lower than 50 for symptom scales. The scores for symptom scales were related to age, renal failure, and disease-free survival. Identification of quality of life and satisfaction of care markers allow for early therapeutic intervention and efficiency and enable a change in quality of life and perception of care in Health Services.<\/jats:p>","DOI":"10.1177\/1073274819831281","type":"journal-article","created":{"date-parts":[[2019,2,21]],"date-time":"2019-02-21T01:15:50Z","timestamp":1550711750000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Health-Related Quality of Life and Satisfaction With Health Care: Relation to Clinical Stage in Mexican Patients With Multiple Myeloma"],"prefix":"10.1177","volume":"26","author":[{"given":"Luz-Ma-Adriana","family":"Balderas-Pe\u00f1a","sequence":"first","affiliation":[{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica 02, Unidad M\u00e9dica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico"},{"name":"Departamento de Morfolog\u00eda, Divisi\u00f3n de Disciplinas B\u00e1sicas para la Salud, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Miranda-Ruvalcaba","sequence":"additional","affiliation":[{"name":"Departamento Cl\u00ednico de Hematolog\u00eda, UMAE, HE, CMNO, IMSS, Guadalajara, Jalisco, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea Isabel","family":"Robles-Espinoza","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica 02, Unidad M\u00e9dica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel","family":"Sat-Mu\u00f1oz","sequence":"additional","affiliation":[{"name":"Departamento de Morfolog\u00eda, Divisi\u00f3n de Disciplinas B\u00e1sicas para la Salud, Centro Universitario de Ciencias de la Salud, Universidad de Guadalajara, Guadalajara, Jalisco, Mexico"},{"name":"Departamento Cl\u00ednico de Oncolog\u00eda Quir\u00fargica, UMAE HE CMNO, IMSS, Guadalajara, Jalisco. Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel Garc\u00e9s","family":"Ruiz","sequence":"additional","affiliation":[{"name":"Departamento Cl\u00ednico de Hematolog\u00eda, UMAE, HE, CMNO, IMSS, Guadalajara, Jalisco, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo","family":"Garc\u00eda-Luna","sequence":"additional","affiliation":[{"name":"Vicerrectoria, Ciencias de la Salud, Universidad de Monterrey, San Pedro Garza Garc\u00eda, N.L, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arnulfo Hernan","family":"Nava-Zavala","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica 02, Unidad M\u00e9dica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico"},{"name":"Programa Internacional de la Facultad de Medicina, Universidad Autonoma de Guadalajara. Jalisco M\u00e9xico"},{"name":"Divisi\u00f3n de Medicina Interna, Servicio de Reumatolog\u00eda e Inmunolog\u00eda Cl\u00ednica, Hospital General de Occidente, Secretaria de Salud Jalisco, Jal, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Benjam\u00edn","family":"Rubio-Jurado","sequence":"additional","affiliation":[{"name":"Unidad de Investigaci\u00f3n Biom\u00e9dica 02, Unidad M\u00e9dica de Alta Especialidad (UMAE), Hospital de Especialidades (HE), Centro M\u00e9dico Nacional de Occidente (CMNO), Instituto Mexicano del Seguro Social (IMSS), Guadalajara, Jalisco, Mexico"},{"name":"Departamento Cl\u00ednico de Hematolog\u00eda, UMAE, HE, CMNO, IMSS, Guadalajara, Jalisco, Mexico"},{"name":"Extension, Consulting and Research Division, Universidad de Monterrey, San Pedro Garza Garc\u00eda, N.L, 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