{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:32:15Z","timestamp":1777483935896,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T00:00:00Z","timestamp":1600646400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012456","name":"National Social Science Foundation of China","doi-asserted-by":"crossref","award":["16BGL183"],"award-info":[{"award-number":["16BGL183"]}],"id":[{"id":"10.13039\/501100012456","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2020,10,1]]},"abstract":"<jats:p>This study aimed to establish and validate a comprehensive nomogram for predicting the cause-specific survival (CSS) probability in tonsillar squamous cell carcinoma (TSCC). We screened and extracted data from the SEER (Surveillance, Epidemiology, and End Results) database for the period 2004 to 2016. We randomly divided the 7243 identified patients into a training cohort (70%) for constructing the model and a validation cohort (30%) for evaluating the model using R software. Multivariate Cox stepwise regression was used to select predictive variables. The concordance index (C-index), the area under the time-dependent receiver operating characteristics curve (AUC), the net reclassification improvement (NRI), the integrated discrimination improvement (IDI), calibration plotting, and decision-curve analysis (DCA) were used to evaluate the model. The multivariate Cox stepwise regression analysis successfully established a nomogram for the 1-, 3-, and 5-year CSS probabilities for TSCC patients. The C-index, AUC, NRI, and IDI were all showed that the model has good discrimination. The calibration plots were very close to the standard lines, indicating that the model has a good degree of calibration, and the DCA curve further illustrated that the model has good clinical validity. We have established the first nomogram for predicting the 1-, 3-, and 5-year CSS probabilities for TSCC based on a large retrospective sample. Our rigorous validation and evaluation indicated that the model can provide useful guidance to clinical workers making clinical decisions about individual patients.<\/jats:p>","DOI":"10.1177\/1073274820960481","type":"journal-article","created":{"date-parts":[[2020,9,21]],"date-time":"2020-09-21T04:00:06Z","timestamp":1600660806000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Establishment and Validation of a Nomogram for Tonsil Squamous Cell Carcinoma: A Retrospective Study Based on the SEER Database"],"prefix":"10.1177","volume":"27","author":[{"given":"Chengzhuo","family":"Li","sequence":"first","affiliation":[{"name":"Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People\u2019s Republic of China"},{"name":"School of Public Health, Xi\u2019an Jiaotong University Health Science Center, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jin","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People\u2019s Republic of China"},{"name":"School of Public Health, Xi\u2019an Jiaotong University Health Science Center, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuai","family":"Zheng","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People\u2019s Republic of China"},{"name":"School of Public Health, Shaanxi University of Chinese Medicine, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengshuo","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People\u2019s Republic of China"},{"name":"School of Public Health, Xi\u2019an Jiaotong University Health Science Center, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Didi","family":"Han","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People\u2019s Republic of China"},{"name":"School of Public Health, Xi\u2019an Jiaotong University Health Science Center, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ling","family":"Bai","sequence":"additional","affiliation":[{"name":"Clinical Research Center, The First Affiliated Hospital of Xi\u2019an Jiaotong University, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuan-long","family":"Wei","sequence":"additional","affiliation":[{"name":"Xi\u2019an an Information Technique Institute of Surveying and Mapping, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shengpeng","family":"Wang","sequence":"additional","affiliation":[{"name":"Cardiovascular Research Center, School of Basic Medical Sciences, Xi\u2019an Jiaotong University Health Science Center, Xi\u2019an, Shaanxi, People\u2019s Republic of China"},{"name":"Key Laboratory of Environment and Genes Related to Diseases of Ministry of Education, Xi\u2019an Jiaotong University Health Science Center, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2237-8771","authenticated-orcid":false,"given":"Jun","family":"Lyu","sequence":"additional","affiliation":[{"name":"Department of Clinical Research, The First Affiliated Hospital of Jinan University, Guangzhou, Guangdong Province, People\u2019s Republic of China"},{"name":"School of Public Health, Xi\u2019an Jiaotong University Health Science Center, Xi\u2019an, Shaanxi, People\u2019s Republic of China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,9,21]]},"reference":[{"key":"bibr1-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70017-6"},{"key":"bibr2-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008918223334"},{"key":"bibr3-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2013.50.3870"},{"key":"bibr4-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.20998"},{"key":"bibr5-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa065497"},{"key":"bibr6-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.1400"},{"key":"bibr7-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1080\/00016480601110170"},{"key":"bibr8-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2008.11.008"},{"key":"bibr9-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198902000-00016"},{"key":"bibr10-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2015.12.017"},{"key":"bibr11-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1159\/000330818"},{"key":"bibr12-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)71116-7"},{"key":"bibr13-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.56.6661"},{"key":"bibr14-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2014.09.019"},{"key":"bibr15-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/j.eururo.2015.01.032"},{"key":"bibr16-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1111\/jebm.12373"},{"key":"bibr17-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1002\/lary.21129"},{"key":"bibr18-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2010121302"},{"key":"bibr19-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1097\/EDE.0b013e3181c30fb2"},{"key":"bibr20-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6947-8-53"},{"key":"bibr21-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-04-0551"},{"key":"bibr22-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2009.03.010"},{"key":"bibr23-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2005.10.018"},{"key":"bibr24-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2009-0289"},{"key":"bibr25-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20796"},{"key":"bibr26-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1002\/hed.24105"},{"key":"bibr27-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27395"},{"key":"bibr28-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2005.05.008"},{"key":"bibr29-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10567"},{"key":"bibr30-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2005.02.025"},{"key":"bibr31-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1148\/radiology.148.3.6878708"},{"key":"bibr32-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2012.41.5984"},{"key":"bibr33-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1007\/s00198-015-3092-3"},{"key":"bibr34-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1002\/sim.4026"},{"key":"bibr35-1073274820960481","doi-asserted-by":"publisher","DOI":"10.1186\/s41512-019-0064-7"}],"container-title":["Cancer Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1073274820960481","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1073274820960481","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1073274820960481","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:21:49Z","timestamp":1777386109000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1073274820960481"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,21]]},"references-count":35,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,10,1]]}},"alternative-id":["10.1177\/1073274820960481"],"URL":"https:\/\/doi.org\/10.1177\/1073274820960481","relation":{},"ISSN":["1073-2748","1526-2359"],"issn-type":[{"value":"1073-2748","type":"print"},{"value":"1526-2359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,9,21]]},"article-number":"1073274820960481"}}