{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,27]],"date-time":"2026-07-27T21:24:00Z","timestamp":1785187440702,"version":"3.55.0"},"reference-count":19,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2022,11,1]],"date-time":"2022-11-01T00:00:00Z","timestamp":1667260800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["MOBJD579"],"award-info":[{"award-number":["MOBJD579"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002301","name":"Eesti Teadusagentuur","doi-asserted-by":"publisher","award":["PRG722"],"award-info":[{"award-number":["PRG722"]}],"id":[{"id":"10.13039\/501100002301","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Cervical cancer incidence and mortality in Estonia are among the highest in Europe, although the overall coverage with cervical cytology is high. This indicates potential issues with the quality of collection and\/or laboratory evaluation of cervical cytology.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>The aim of the retrospective observational study was to assess the quality of cervical cytology specimen collection, evaluation, and reporting using laboratory reports in Estonia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The study included women with a cervical cancer diagnosis in 2017\u22122018. Cervical cytology and histology reports for these women in 2007\u22122018 were obtained from ten laboratories. We described the quality of cytology specimen collection and reporting of cytology results. Multivariate logistic regression was used to calculate odds ratios (OR) with 95% confidence intervals (CI) to identify factors associated with NILM as the last cervical cytology result within 5 or 2\u00a0years before the cervical cancer diagnosis. Also, we calculated cytology-histology correlation (CHC).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We identified 503 cytology and 100 histology reports from 138 women. The laboratories differed greatly regarding human resources, work capacity and volume. Differences between local and regional laboratories were observed in reporting specimen adequacy (P &lt; .001). We found that local laboratories had 3 times higher odds (OR = 2.95, 95% CI: 1.05\u22128.33) of reporting normal results 2\u00a0years before cancer diagnosis than regional laboratories. According to the CHC, 58.9% of pairs were in agreement.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The study showed considerable heterogeneity and suboptimal performance of cervical cytology practices in Estonia, particularly at local laboratories. Efforts to improve laboratory quality assurance are crucial.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10732748221141794","type":"journal-article","created":{"date-parts":[[2022,12,21]],"date-time":"2022-12-21T14:51:32Z","timestamp":1671634292000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Quality Assessment of Cervical Cytology Practices in Estonia From 2007 to 2018"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6849-202X","authenticated-orcid":false,"given":"Madleen","family":"Orumaa","sequence":"first","affiliation":[{"name":"Department of Epidemiology and Biostatistics, National Institute for Health Development, Tallinn, Estonia"},{"name":"Department of Research, Cancer Registry of Norway, Oslo University Hospital, Oslo, Norway"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0120-2213","authenticated-orcid":false,"given":"Kaire","family":"Innos","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, National Institute for Health Development, Tallinn, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Suurna","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, National Institute for Health Development, Tallinn, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liis","family":"Salum\u00e4e","sequence":"additional","affiliation":[{"name":"Pathology Department of Tartu University Hospital, Tartu, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Piret","family":"Veerus","sequence":"additional","affiliation":[{"name":"Department of Epidemiology and Biostatistics, National Institute for Health Development, Tallinn, Estonia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,12,21]]},"reference":[{"key":"bibr1-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-018-5006-1"},{"key":"bibr2-10732748221141794","unstructured":"ECIS - European Cancer Information System. https:\/\/ecis.jrc.ec.europa.eu. https:\/\/ecis.jrc.ec.europa.eu. Accessed 21.09.2022."},{"key":"bibr3-10732748221141794","volume-title":"VSR12: Cervical Cancer Screening Coverage by PAP-Test Examination in Target Population by Age"},{"key":"bibr4-10732748221141794","volume-title":"TG06: Use of 'Laboratory Tests\u2019 by Contractor","year":"2021"},{"key":"bibr5-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1097\/01.mlr.0000128007.04494.29"},{"key":"bibr6-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2303.2008.00623.x"},{"key":"bibr7-10732748221141794","unstructured":"Diagnosis, monitoring and treatment of pre-cancerous changes in the cervix, vagina and vulva. HPV vaccination recommendations. 4th verison. 2021."},{"key":"bibr8-10732748221141794","volume-title":"European Guidelines for Quality Assurance in Cervical Cancer Screening","author":"Arbyn M","year":"2015"},{"key":"bibr9-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-11074-5"},{"key":"bibr10-10732748221141794","volume-title":"WHO Classification of Tumours of Female Reproductive Organs","year":"2014"},{"issue":"6","key":"bibr11-10732748221141794","first-page":"330","volume":"94","author":"Orumaa M","year":"2015","journal-title":"Eesti Arst"},{"key":"bibr12-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12774"},{"key":"bibr13-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.3857"},{"key":"bibr14-10732748221141794","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-147-8-200710160-00010"},{"key":"bibr15-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-020-02894-6"},{"key":"bibr16-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1159\/000513899"},{"key":"bibr17-10732748221141794","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2004.0050"},{"key":"bibr18-10732748221141794","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics12010210"},{"key":"bibr19-10732748221141794","doi-asserted-by":"publisher","DOI":"10.1111\/cyt.12057"}],"container-title":["Cancer Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10732748221141794","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10732748221141794","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10732748221141794","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:22:58Z","timestamp":1777386178000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10732748221141794"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11]]},"references-count":19,"alternative-id":["10.1177\/10732748221141794"],"URL":"https:\/\/doi.org\/10.1177\/10732748221141794","relation":{},"ISSN":["1073-2748","1526-2359"],"issn-type":[{"value":"1073-2748","type":"print"},{"value":"1526-2359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11]]},"article-number":"10732748221141794"}}