{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:45:10Z","timestamp":1777484710947,"version":"3.51.4"},"reference-count":47,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>Identify predictors of overall survival (OS) after hypopharyngeal\/laryngeal cancer in Florida.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Material and Methods<\/jats:title>\n                    <jats:p>We conducted a retrospective cohort study using data from the Florida Cancer Data System (FCDS) on patients diagnosed with hypopharyngeal or laryngeal cancer from 2010-2017. Primary outcome was OS. Hazard ratios (HRs) were estimated from univariable and multivariable Cox regression models for OS. Data was analyzed from November 1, 2022, to June 30, 2023.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>We analyzed 6771 patients, who were primarily male (81.2%), White non-Hispanic (WNH) (78.2%), publicly insured (70.1%), married (51.8%), and residents of urban counties (73.6%). Black patients were more likely to be younger at diagnosis (38.9%), single (43.4%), to have distant SEER stage disease (25.6%). Median OS were lowest among patients who were uninsured (34 months), with hypopharyngeal site disease (18 months), and a smoking history (current: 34 months, former: 46 months, no smoking: 63 months). Multivariable Cox regression analysis showed worse OS for single\/unmarried vs married (HR 1.47 [95%CI: 1.36-1.59], P &lt; .001), history of tobacco use (current: HR 1.62 [95%CI: 1.440-1.817], P &lt; .001; former smokers: (HR 1.28 [95%CI: 1.139-1.437], P &lt; .001) vs no history). Improved OS was observed among White Hispanics (WH) vs WNH (HR .73 [95%CI: .655-.817], P &lt; .001) and women vs men (HR .88 [95%CI: .807-.954], P = .002). Geographical mapping showed that mortality rates were highest in census tracts with low income and education.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Our findings suggest that sociodemographic and clinical factors impact OS from hypopharyngeal\/laryngeal cancer in Florida and vary geographically within the state. These results will help guide future public health interventions.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10732748241246958","type":"journal-article","created":{"date-parts":[[2024,4,16]],"date-time":"2024-04-16T06:37:16Z","timestamp":1713249436000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Investigating Disparities in Hypopharyngeal\/Laryngeal Cancer Survival in Florida With Geospatial Mapping Analysis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8860-6319","authenticated-orcid":false,"given":"Uche C.","family":"Ezeh","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdurrahman","family":"Al-Awady","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0897-0429","authenticated-orcid":false,"given":"Isabella","family":"Buitron","sequence":"additional","affiliation":[{"name":"New York University, New York, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Lee","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garrett","family":"Forman","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sophia","family":"Peifer","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alana","family":"Deo","sequence":"additional","affiliation":[{"name":"University of California Santa Barbara, Santa Barbara, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larissa","family":"Sweeny","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Donald","family":"Weed","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Erin K.","family":"Kobetz","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isildinha M","family":"Reis","sequence":"additional","affiliation":[{"name":"Division of Biostatistics, Department of Public Health Sciences, Sylvester Biostatistics and Bioinformatics Shared Resource, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elizabeth","family":"Franzmann","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2013Head and Neck Surgery, University of Miami Miller School of Medicine, Miami, FL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,16]]},"reference":[{"key":"bibr1-10732748241246958","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21763"},{"key":"bibr2-10732748241246958","first-page":"729","volume-title":"Rosenberg\u2019s Cancer: Principles and Practice of Oncology","author":"Mendenhall W","year":"2011"},{"key":"bibr3-10732748241246958","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21613"},{"key":"bibr4-10732748241246958","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-20-0036"},{"key":"bibr5-10732748241246958","unstructured":"Survival rates for laryngeal and hypopharyngeal cancers. 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Florida Cancer Data System. https:\/\/apps.who.int\/iris\/handle\/10665\/96612. 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