{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T21:46:58Z","timestamp":1791928018020,"version":"4.3.4"},"reference-count":29,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Splenic flexure adenocarcinoma poses unique challenges in surgical management due to its location and lymphatic drainage. This study compared the efficacy and oncological safety of extended right hemicolectomy (ERC) and left colectomy (LC) for treating this condition.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This study followed the PRISMA and AMSTAR 2 guidelines. Key outcomes included postoperative mortality, morbidity, severe complications, operative results, pathological findings (R0 resection, lymph nodes), and oncological results (overall survival and disease-free survival at 3 and 5\u00a0years).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Twelve non-randomised studies were included involving 1710 patients (713 ERC group, 997 LC group). The analysis showed that ERC was associated with more lymph nodes and a lower conversion rate. However, there were no significant differences between ERC and LC in terms of mortality, morbidity, severe complications, anastomotic leak, wound infection, ileus, reoperation, R0 resection, hospital stay, and overall and disease-free survival rates.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>ERC and LC are comparable in terms of postoperative and long-term oncological outcomes for splenic flexure adenocarcinoma, with ERC potentially producing a higher lymph node harvest rate and a lower conversion rate. ERC could be suggested for a better stage of the disease and when the surgical team considers the laparoscopic approach.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10732748241287019","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T01:10:30Z","timestamp":1726881030000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":8,"title":["Comparative Efficacy and Long-Term Oncological Safety of Extended Right Hemicolectomy Versus Left Colectomy for Splenic Flexure Adenocarcinoma: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9013-5229","authenticated-orcid":false,"given":"Mohamed Ali","family":"Chaouch","sequence":"first","affiliation":[{"name":"Department of Visceral and Digestive Surgery, Fattouma Bourguiba Hospital, University of Monastir, Monastir, Tunisia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bassem","family":"Krimi","sequence":"additional","affiliation":[{"name":"Department of Surgery, Perpignan Hospital Center, Perpignan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amine","family":"Gouader","sequence":"additional","affiliation":[{"name":"Department of Surgery, Perpignan Hospital Center, Perpignan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanen","family":"Bhiri","sequence":"additional","affiliation":[{"name":"Department of Oncology, Perpignan Hospital Center, Perpignan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elise","family":"Barel","sequence":"additional","affiliation":[{"name":"Department of Oncology, Perpignan Hospital Center, Perpignan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Faiza Khemissa","family":"Akouz","sequence":"additional","affiliation":[{"name":"Department of Gastroenterology and Hepatology, Perpignan Hospital Center, Perpignan, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,9,20]]},"reference":[{"key":"bibr1-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1111\/codi.15292"},{"key":"bibr2-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1097\/SLE.0000000000000419"},{"key":"bibr3-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2021.02.003"},{"key":"bibr4-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.j4008"},{"key":"bibr5-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000133083.54934.ae"},{"key":"bibr6-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-2197.2003.02748.x"},{"key":"bibr7-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2010.07.015"},{"key":"bibr8-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"bibr9-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.315.7109.629"},{"key":"bibr10-10732748241287019","volume-title":"Cochrane Handbook for Systematic Reviews of Interventions"},{"issue":"9","key":"bibr11-10732748241287019","first-page":"1201","volume":"33","author":"Mart\u00edn Ar\u00e9valo J","year":"2018","journal-title":"Sept"},{"key":"bibr12-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1089\/lap.2019.0041"},{"key":"bibr13-10732748241287019","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2017.06.035"},{"key":"bibr14-10732748241287019","first-page":"3089","volume":"6","author":"Bono D","year":"2021","journal-title":"Short-Term and Long-Term Outcomes. 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