{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T17:46:28Z","timestamp":1777484788759,"version":"3.51.4"},"reference-count":50,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Delirium is a common neuropsychiatric syndrome in hospitalized cancer patients that is associated with poor outcomes such as increased mortality and prolonged hospital stays. However, clinical predictors of delirium-related outcomes in acutely hospitalized, non-surgical cancer patients remain underexplored.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a retrospective cohort study of hospitalized cancer patients at a tertiary-care oncology center between May 2024 and August 2024 who developed delirium. Delirium was defined by a positive Confusion Assessment Method (CAM) screen. Patients who were admitted for surgical reasons or had an altered mental status (AMS) present on admission were excluded. Patient demographics and clinical factors associated with their hospital course were abstracted from electronic medical records. Primary outcomes analyzed were in-hospital mortality, delirium duration, and length of stay (LOS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 126 patients met the inclusion criteria from a screening pool of 219 patients. The median age was 65.5 years (IQR: 58,73) and 65 patients (51.6%) were male. Nearly half (43.7%) had hematologic malignancies. Twenty patients (15.9%) died during hospitalization. Non-survivors had significantly lower albumin (3.0 vs 3.5\u00a0g\/dL,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01), platelets (86 vs 190 \u00d7 10\n                      <jats:sup>3<\/jats:sup>\n                      \/\u00b5L,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.031), BMI (23.3 vs 27.1\u00a0kg\/m\n                      <jats:sup>2<\/jats:sup>\n                      ,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.046), and higher LDH (515 vs 273\u00a0U\/L,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.044). They also experienced delirium for longer (median 3 vs 1 days,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.011), had a higher incidence of sepsis (27% vs 14%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.015), and received more benzodiazepines before delirium onset (0.152 vs 0.045\u00a0mg\/day,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.040). Prolonged delirium (&gt;1\u00a0day) was associated with similar factors. LOS positively correlated with delirium duration and sedative exposure, and inversely with hemoglobin and platelet counts.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Delirium in hospitalized cancer patients may reflect underlying physiological frailty that increases susceptibility to mortality from metabolic derangements, malnutrition, sepsis, and sedative exposure. Early identification of these high-risk clinical factors in cancer inpatients with delirium may help mitigate risks posed by these abnormalities.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10732748251411005","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T07:06:15Z","timestamp":1767683175000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Incident Delirium in Hospitalized Cancer Patients: Clinical Factors Associated With Mortality and Prolonged Hospitalization"],"prefix":"10.1177","volume":"33","author":[{"ORCID":"https:\/\/orcid.org\/0009-0003-9106-0438","authenticated-orcid":false,"given":"Brandon","family":"Dyer","sequence":"first","affiliation":[{"name":"Morsani College of Medicine, University of South Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6691-521X","authenticated-orcid":false,"given":"Joel","family":"Kallarackal","sequence":"additional","affiliation":[{"name":"Morsani College of Medicine, University of South Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Baldwin","sequence":"additional","affiliation":[{"name":"Morsani College of Medicine, University of South Florida"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aasha","family":"Hoogland","sequence":"additional","affiliation":[{"name":"Moffitt Cancer Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kenneth","family":"Snell","sequence":"additional","affiliation":[{"name":"Moffitt Cancer Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heather","family":"Jim","sequence":"additional","affiliation":[{"name":"Moffitt Cancer Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey","family":"Huang","sequence":"additional","affiliation":[{"name":"Moffitt Cancer Center"},{"name":"Moffitt Cancer Center"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,1,5]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-020-00223-4"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425787"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)60688-1"},{"key":"e_1_3_6_5_2","first-page":"289","article-title":"Transient cognitive disorders (delirium, acute confusional sates) in the elderly","volume":"140","author":"Lipowski Z","year":"1985","unstructured":"Lipowski Z, Lipowski Z. 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