{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,17]],"date-time":"2026-07-17T14:15:16Z","timestamp":1784297716856,"version":"3.55.0"},"reference-count":37,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100000054","name":"National Cancer Institute","doi-asserted-by":"publisher","award":["P30CA240139"],"award-info":[{"award-number":["P30CA240139"]}],"id":[{"id":"10.13039\/100000054","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>While race\/ethnicity are established factors of risk and outcomes for multiple cancers in women, nativity may more precisely estimate cancer risk and survival. The role of nativity in choriocarcinoma, a form of gestational trophoblastic neoplasia arising from the placenta, is unexplored. Our objective was to examine how race, ethnicity, and nativity influence disease presentation and survival in women with choriocarcinoma in Florida.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>\n                      Using the Florida Cancer Data System (FCDS), we identified women diagnosed with choriocarcinoma from 1981-2020. Clinicodemographic data were extracted, including nativity (US-born\/Non-US-born). Statistical analyses included chi-square, Cox proportional hazards models, and Kaplan-Meier method, with significance set at\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      262 eligible patients were included. Black women more frequently presented with distant disease vs White women (63.8% vs 46.2%,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.05). Non-US-Born women were older at diagnosis than US-born (32.8 vs 26.7\u00a0years,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.01) and received fewer surgical and radiation treatments (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; 0.05). Nativity, ethnicity, and race were not associated with overall survival (OS) (all\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05). Multivariable analyses adjusted for race and birthplace showed increasing age (HR 1.05 [1.02-1.09],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.023) and surgical treatment (HR 0.28 [0.09-0.79],\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = 0.016) were associated with OS. Despite favorable OS, survival curves diverged after initial treatment, favoring White over Black patients, and Hispanic over Non-Hispanic patients, though neither were statistically significant (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &gt; 0.05).\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Race and nativity are associated with variations in choriocarcinoma presentation and treatment course but do not affect survival. Race and ethnicity may predict post-treatment, long-term survival, though whether this reflects choriocarcinoma biology or broader disparities remain unclear.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10732748251413803","type":"journal-article","created":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T07:06:17Z","timestamp":1767683177000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Influence of Race, Ethnicity, and Nativity on Distribution and Outcomes Among Women With Choriocarcinoma in Florida"],"prefix":"10.1177","volume":"33","author":[{"given":"Claud","family":"Crosby","sequence":"first","affiliation":[{"name":"Sylvester Comprehensive Cancer Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0474-992X","authenticated-orcid":false,"given":"Alex","family":"Sanchez-Covarrubias","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jovanka","family":"Ravix","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Navya","family":"Nair","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdulrahman","family":"Sinno","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maurice","family":"Chery","sequence":"additional","affiliation":[{"name":"University of Miami Miller School of Medicine"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia H. L.","family":"George","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0257-7327","authenticated-orcid":false,"given":"Matthew","family":"Schlumbrecht","sequence":"additional","affiliation":[{"name":"Sylvester Comprehensive Cancer Center"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,1,5]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2021.10.003"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000001156"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2021.0307"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.699577"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2017.09.002"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2020.00880"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.lana.2025.101292"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2023.07.008"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2015.04.030"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1007108"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.70275"},{"key":"e_1_3_5_13_2","unstructured":"Prenatal Care_Florida Department of Health. https:\/\/www.floridahealth.gov\/programs-and-services\/womens-health\/pregnancy\/prenatal-care.html Accessed September 6."},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1177\/10732748231176642"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2020.7665"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamasurg.2018.0035"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-15-0316"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1093\/jncics\/pkz084"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.32451"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.4954"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000004224"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000003728"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamahealthforum.2021.1054"},{"key":"e_1_3_5_24_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21731"},{"key":"e_1_3_5_25_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.17322"},{"key":"e_1_3_5_26_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2021.07.022"},{"key":"e_1_3_5_27_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2017.07.145"},{"key":"e_1_3_5_28_2","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph21030324"},{"key":"e_1_3_5_29_2","doi-asserted-by":"publisher","DOI":"10.17849\/insm-47-03-143-158.1"},{"key":"e_1_3_5_30_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-019-05403-9"},{"key":"e_1_3_5_31_2","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.7449"},{"key":"e_1_3_5_32_2","doi-asserted-by":"publisher","DOI":"10.1136\/ijgc-2019-000347"},{"key":"e_1_3_5_33_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(25)00207-4"},{"key":"e_1_3_5_34_2","doi-asserted-by":"publisher","DOI":"10.1080\/07347332.2022.2154730"},{"key":"e_1_3_5_35_2","doi-asserted-by":"publisher","DOI":"10.1080\/08964289.2019.1585326"},{"key":"e_1_3_5_36_2","unstructured":"Jordan J. New estimates highlight differences in growthn between the U.S. Hispanic and non-Hispanic populations. https:\/\/www.census.gov\/newsroom\/press-releases\/2024\/population-estimates-characteristics.html. Accessed 28 November."},{"key":"e_1_3_5_37_2","unstructured":"FLORIDA: 2020 Census. https:\/\/www.census.gov\/library\/stories\/state-by-state\/florida.html#race-ethnicity. Accessed 17 November."},{"key":"e_1_3_5_38_2","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.epirev.a036275"}],"container-title":["Cancer Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10732748251413803","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10732748251413803","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10732748251413803","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:24:20Z","timestamp":1777386260000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10732748251413803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":37,"alternative-id":["10.1177\/10732748251413803"],"URL":"https:\/\/doi.org\/10.1177\/10732748251413803","relation":{"has-review":[{"id-type":"doi","id":"10.1177\/10732748251413803\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748251413803\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748251413803\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748251413803\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748251413803\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748251413803\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748251413803\/v2\/response1","asserted-by":"object"}]},"ISSN":["1073-2748","1526-2359"],"issn-type":[{"value":"1073-2748","type":"print"},{"value":"1526-2359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1]]},"article-number":"10732748251413803"}}