{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T12:30:48Z","timestamp":1777984248554,"version":"3.51.4"},"reference-count":37,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"The Development Fund of Xuzhou Medical University Affiliated Hospital","award":["XYFM202426"],"award-info":[{"award-number":["XYFM202426"]}]},{"name":"The Development Fund of Xuzhou Medical University Affiliated Hospital","award":["XYFZ202404"],"award-info":[{"award-number":["XYFZ202404"]}]},{"name":"The Science and Technology Development Program of Suzhou","award":["SYWD2024077"],"award-info":[{"award-number":["SYWD2024077"]}]},{"name":"The Science and Technology Development Program of Suzhou","award":["SYWD2024322"],"award-info":[{"award-number":["SYWD2024322"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The prognosis differences of gastrointestinal stromal tumors (GISTs) between the jejunum and ileum have rarely been studied. This study aimed to evaluate the long-term survival outcomes in patients with jejunal and ileal GISTs.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This population-based retrospective cohort study utilized data from the Surveillance, Epidemiology, and End Results (SEER) database from 2000 to 2019. Kaplan-Meier analyses and Cox proportional hazards models were employed to assess overall survival (OS) and cancer-specific survival (CSS). A 1:1 propensity score matching (PSM) approach was implemented to address confounding factors, and subgroup analyses were performed for various variables.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 1237 patients were analyzed, with 848 in the jejunum and 389 in the ileum. Ileal GISTs patients were older, exhibited higher T stages, larger tumor sizes, elevated mitotic rates, and were more susceptible to distant metastasis (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt;0.05). After PSM, the jejunal GISTs group and the ileal GISTs group demonstrated comparable OS (hazard ratio [HR]: 1.25, 95% confidence interval [CI]: 0.97-1.60,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.082) and CSS (HR: 1.13, 95% CI: 0.81-1.59,\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      =0.461). Additionally, jejunal GISTs and ileal GISTs exhibited similar OS and CSS across various subgroups. Multivariate Cox regression analysis revealed age, TNM stage, and mitotic rate as independent risk factors influencing OS, whereas race, N stage, and M stage were identified as independent risk factors affecting CSS.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Jejunal GISTs and ileal GISTs have comparable OS and CSS, with the occurrence of lymph node metastasis and distant metastasis being important factors affecting their prognosis.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10732748261442634","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T12:52:42Z","timestamp":1775652762000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Long-Term Prognosis Analysis of Gastrointestinal Stromal Tumors in the Jejunum and Ileum: A SEER-Based Study"],"prefix":"10.1177","volume":"33","author":[{"given":"Xiaochun","family":"Lu","sequence":"first","affiliation":[{"name":"Suzhou Ninth People\u2019s Hospital"},{"name":"The Affiliated Suzhou Bay Clinical College of Xuzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong","family":"Liu","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Soochow University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shimeng","family":"Zhang","sequence":"additional","affiliation":[{"name":"Suzhou Ninth People\u2019s Hospital"},{"name":"The Affiliated Suzhou Bay Clinical College of Xuzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuaiyang","family":"Zhou","sequence":"additional","affiliation":[{"name":"Suzhou Ninth People\u2019s Hospital"},{"name":"The Affiliated Suzhou Bay Clinical College of Xuzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rencheng","family":"Cai","sequence":"additional","affiliation":[{"name":"Gaochun People\u2019s Hospital of Nanjing"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9079-956X","authenticated-orcid":false,"given":"Zhenguo","family":"Qiao","sequence":"additional","affiliation":[{"name":"Suzhou Ninth People\u2019s Hospital"},{"name":"The Affiliated Suzhou Bay Clinical College of Xuzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tinghua","family":"Cao","sequence":"additional","affiliation":[{"name":"Suzhou Ninth People\u2019s Hospital"},{"name":"The Affiliated Suzhou Bay Clinical College of Xuzhou Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2026,4,8]]},"reference":[{"key":"e_1_3_6_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00254-5"},{"key":"e_1_3_6_3_2","doi-asserted-by":"publisher","DOI":"10.1053\/j.semdp.2006.09.001"},{"key":"e_1_3_6_4_2","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2022.0058"},{"key":"e_1_3_6_5_2","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-22-3980"},{"key":"e_1_3_6_6_2","doi-asserted-by":"publisher","DOI":"10.1586\/14737140.2015.1032941"},{"key":"e_1_3_6_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-023-04548-w"},{"key":"e_1_3_6_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2013.11.029"},{"key":"e_1_3_6_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2015.06.027"},{"key":"e_1_3_6_10_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2021.01.004"},{"key":"e_1_3_6_11_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-023-14346-x"},{"key":"e_1_3_6_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-023-05706-9"},{"key":"e_1_3_6_13_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-023-10433-y"},{"key":"e_1_3_6_14_2","doi-asserted-by":"publisher","DOI":"10.2147\/CMAR.S278612"},{"key":"e_1_3_6_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000807"},{"key":"e_1_3_6_16_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-46520-1"},{"key":"e_1_3_6_17_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200604000-00008"},{"key":"e_1_3_6_18_2","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000146010.92933.de"},{"key":"e_1_3_6_19_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2982.2012.01955.x"},{"issue":"101","key":"e_1_3_6_20_2","first-page":"777","article-title":"Are there any functional differences of the enteric nervous system between jejunum and ileum in normal humans?","volume":"57","author":"Tomita R","year":"2010","unstructured":"Tomita R, Igarashi S, Fujisaki S, Koshinaga T, Kusafuka T. 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