{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T14:04:02Z","timestamp":1789740242354,"version":"4.0.1"},"reference-count":47,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82273348"],"award-info":[{"award-number":["82273348"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Scientific Research Fund of Zhejiang Provincial Education Department","award":["Y202454712"],"award-info":[{"award-number":["Y202454712"]}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2704200"],"award-info":[{"award-number":["2022YFC2704200"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2022YFC2704203"],"award-info":[{"award-number":["2022YFC2704203"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017599","name":"Science and Technology Program of Zhejiang Province","doi-asserted-by":"publisher","award":["2024C03159"],"award-info":[{"award-number":["2024C03159"]}],"id":[{"id":"10.13039\/501100017599","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Cancer Control"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Lymphocele is a common complication following gynecologic cancer surgery. Given that lymphadenectomy for ovarian cancer differs from that for other gynecologic malignancies, it is essential to determine whether the risk factors for postoperative lymphocele are specific to this patient population.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Method<\/jats:title>\n                    <jats:p>A Delphi study was conducted to identify risk factors for postoperative lymphocele in ovarian cancer and to establish eligibility criteria for an institutional development cohort. Based on these findings, we retrospectively collected clinicopathological data from patients who underwent ovarian cancer staging surgery at our institution between 2019 and 2024. Postoperative lymphocele and baseline clinical variables were compared using chi-square tests and regression analyses. A nomogram for predicting lymphocele risk was developed using the least absolute shrinkage and selection operator (LASSO) method, and its performance was evaluated using calibration curves and decision curve analysis (DCA).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Following three rounds of the Delphi survey, 13 risk factors met the criteria for expert consensus and boundary definition. Among 324 patients with ovarian cancer, multivariate analysis revealed that open surgery, a higher number of retrieved lymph nodes, and adjuvant therapy were independently associated with lymphocele. LASSO regression selected age, hypertension, diabetes, anemia, surgical approach, lymphadenectomy details (number and extent), lymph node metastasis, drainage, and adjuvant therapy as predictors for the nomogram. The model demonstrated good predictive performance (C-index: 0.784), which was confirmed by calibration and decision curve analyses.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>By incorporating the Delphi method into the development of our prediction model, we achieved a more comprehensive identification of risk factors for postoperative lymphocele in ovarian cancer than previously reported. We anticipate that this innovative model will facilitate broader adoption in future clinical practice and research.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10732748261490458","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T11:54:13Z","timestamp":1789559653000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Ovarian Cancer Lymphocele Risk: A Delphi-Based Retrospective Model Development and Validation"],"prefix":"10.1177","volume":"33","author":[{"given":"Lingjia","family":"Lu","sequence":"first","affiliation":[{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1450-1936","authenticated-orcid":false,"given":"Tao","family":"Zhang","sequence":"additional","affiliation":[{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingfan","family":"Zhu","sequence":"additional","affiliation":[{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"},{"name":"Zhejiang University Clinical Medical Research Center"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhao","sequence":"additional","affiliation":[{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiali","family":"Xu","sequence":"additional","affiliation":[{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingyi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Chongqing Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chanyuan","family":"Li","sequence":"additional","affiliation":[{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"},{"name":"Harvard University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaodong","family":"Wu","sequence":"additional","affiliation":[{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6073-7261","authenticated-orcid":false,"given":"Xiaodong","family":"Cheng","sequence":"additional","affiliation":[{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"},{"name":"Zhejiang Provincial Clinical Research Center for Obstetrics and Gynecology"},{"name":"Women\u2019s Hospital, School of Medicine, Zhejiang University"},{"name":"Zhejiang Provincial Key Laboratory of Traditional Chinese Medicine for Reproductive Health Research"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,9,16]]},"reference":[{"issue":"6","key":"e_1_3_7_2_2","first-page":"CD007387","article-title":"Retroperitoneal drainage versus no drainage after pelvic lymphadenectomy for the prevention of lymphocyst formation in women with gynaecological malignancies","volume":"6","author":"Charoenkwan K","year":"2017","unstructured":"Charoenkwan K, Kietpeerakool C. Retroperitoneal drainage versus no drainage after pelvic lymphadenectomy for the prevention of lymphocyst formation in women with gynaecological malignancies. Cochrane Database Syst Rev. 2017;6(6):CD007387.","journal-title":"Cochrane Database Syst Rev"},{"key":"e_1_3_7_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.70377"},{"key":"e_1_3_7_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/IGC.0000000000000353"},{"key":"e_1_3_7_5_2","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.20110"},{"key":"e_1_3_7_6_2","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2012-0088"},{"issue":"2","key":"e_1_3_7_7_2","first-page":"243","article-title":"Retroperitoneal drainage after complete Para-aortic lymphadenectomy for gynecologic cancer: a randomized trial","volume":"97","author":"Morice P","year":"2001","unstructured":"Morice P, Lassau N, Pautier P, Haie-Meder C, Lhomme C, Castaigne D. Retroperitoneal drainage after complete Para-aortic lymphadenectomy for gynecologic cancer: a randomized trial. Obstet Gynecol. 2001;97(2):243-247.","journal-title":"Obstet Gynecol"},{"key":"e_1_3_7_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2015.02.016"},{"key":"e_1_3_7_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0090-8258(88)90240-5"},{"key":"e_1_3_7_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyd107"},{"key":"e_1_3_7_11_2","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2004.36.6.377"},{"key":"e_1_3_7_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2012.10.011"},{"key":"e_1_3_7_13_2","doi-asserted-by":"publisher","DOI":"10.1002\/ijgo.70282"},{"key":"e_1_3_7_14_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2025.9495"},{"key":"e_1_3_7_15_2","doi-asserted-by":"publisher","DOI":"10.14740\/wjon1824"},{"key":"e_1_3_7_16_2","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2022.33.e69"},{"issue":"5","key":"e_1_3_7_17_2","first-page":"388","article-title":"Incidence and therapy of lymphoceles after pelvic and paraaortic lymph node dissection \u2013 our file","volume":"79","author":"Felsingerov\u00e1 Z","year":"2014","unstructured":"Felsingerov\u00e1 Z, Min\u00e1\u0159 L, Weinberger V. Incidence and therapy of lymphoceles after pelvic and paraaortic lymph node dissection \u2013 our file. Ceska Gynekol. 2014;79(5):388-392.","journal-title":"Ceska Gynekol"},{"key":"e_1_3_7_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2017.03.014"},{"issue":"1","key":"e_1_3_7_19_2","first-page":"10","article-title":"The Delphi technique: making sense of consensus","volume":"12","author":"Hsu CC","year":"2007","unstructured":"Hsu CC, Sandford BA. The Delphi technique: making sense of consensus. Practical assessment, research, and evaluation. 2007;12(1):10.","journal-title":"Practical assessment, research, and evaluation"},{"key":"e_1_3_7_20_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2648.2000.t01-1-01567.x"},{"key":"e_1_3_7_21_2","doi-asserted-by":"publisher","DOI":"10.2147\/CCID.S345005"},{"key":"e_1_3_7_22_2","doi-asserted-by":"publisher","DOI":"10.1186\/s41256-024-00367-w"},{"key":"e_1_3_7_23_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12889-023-15262-1"},{"key":"e_1_3_7_24_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.acra.2015.08.003"},{"key":"e_1_3_7_25_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2023-078276"},{"key":"e_1_3_7_26_2","doi-asserted-by":"publisher","DOI":"10.1136\/bmj-2023-078378"},{"key":"e_1_3_7_27_2","doi-asserted-by":"publisher","DOI":"10.1002\/sim.3148"},{"key":"e_1_3_7_28_2","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(14)71116-7"},{"key":"e_1_3_7_29_2","doi-asserted-by":"publisher","DOI":"10.21037\/tcr-2025-850"},{"key":"e_1_3_7_30_2","doi-asserted-by":"publisher","DOI":"10.5468\/ogs.2017.60.5.440"},{"key":"e_1_3_7_31_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2023.12.010"},{"key":"e_1_3_7_32_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a041173"},{"key":"e_1_3_7_33_2","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a041274"},{"key":"e_1_3_7_34_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-021-08984-1"},{"key":"e_1_3_7_35_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-018-4914-2"},{"issue":"11","key":"e_1_3_7_36_2","first-page":"1193","article-title":"Influences of lymphatic vessel ligation in pelvic lymphadenectomy on postoperative lymphocyst formation\u2014a randomized controlled trial","volume":"28","author":"Lu HW","year":"2009","unstructured":"Lu HW, Zhou H, Peng YP, et al. Influences of lymphatic vessel ligation in pelvic lymphadenectomy on postoperative lymphocyst formation\u2014a randomized controlled trial. Ai Zheng. 2009;28(11):1193-1197.","journal-title":"Ai Zheng"},{"key":"e_1_3_7_37_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2009.05.026"},{"key":"e_1_3_7_38_2","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1096-9098(199807)68:3<149::AID-JSO3>3.0.CO;2-5"},{"key":"e_1_3_7_39_2","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-015-4613-1"},{"key":"e_1_3_7_40_2","doi-asserted-by":"publisher","DOI":"10.3390\/nu14235183"},{"issue":"2","key":"e_1_3_7_41_2","first-page":"136","article-title":"Digestive toxicity in cancer treatments. Bibliographic review. Influence on nutritional status","volume":"70","author":"Alonso Dominguez T","year":"2023","unstructured":"Alonso Dominguez T, Civera AM, Santiago Crespo JA, Garcia Malpartida K, Botella Romero F. Digestive toxicity in cancer treatments. Bibliographic review. Influence on nutritional status. Endocrinol Diabetes Nutr (Engl Ed). 2023;70(2):136-150.","journal-title":"Endocrinol Diabetes Nutr (Engl Ed)"},{"key":"e_1_3_7_42_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2024.107938"},{"key":"e_1_3_7_43_2","doi-asserted-by":"publisher","DOI":"10.3802\/jgo.2017.28.e37"},{"key":"e_1_3_7_44_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmig.2014.12.007"},{"key":"e_1_3_7_45_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejogrb.2015.12.005"},{"key":"e_1_3_7_46_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijgo.2011.12.021"},{"key":"e_1_3_7_47_2","doi-asserted-by":"publisher","DOI":"10.21037\/gs-2019-ursoc-10"},{"key":"e_1_3_7_48_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00270-006-0180-y"}],"container-title":["Cancer Control"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10732748261490458","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10732748261490458","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10732748261490458","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T13:16:56Z","timestamp":1789737416000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10732748261490458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":47,"alternative-id":["10.1177\/10732748261490458"],"URL":"https:\/\/doi.org\/10.1177\/10732748261490458","relation":{"has-review":[{"id-type":"doi","id":"10.1177\/10732748261490458\/v3\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v2\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v1\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v1\/review3","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v1\/review2","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v1\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v2\/review1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v2\/response1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v2\/decision1","asserted-by":"object"},{"id-type":"doi","id":"10.1177\/10732748261490458\/v3\/decision1","asserted-by":"object"}]},"ISSN":["1073-2748","1526-2359"],"issn-type":[{"value":"1073-2748","type":"print"},{"value":"1526-2359","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9]]},"article-number":"10732748261490458"}}