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However, in some individuals with LBP, adapted motor control strategies might have long-term consequences, such as increased spinal loading that has been linked with degeneration of intervertebral discs and other tissues, potentially maintaining recurrent or chronic LBP. Factors contributing to motor control adaptations in LBP have been extensively studied on the motor output side, but less attention has been paid to changes in sensory input, specifically proprioception. Furthermore, motor cortex reorganization has been linked with chronic and recurrent LBP, but underlying factors are poorly understood. Here, we review current research on behavioral and neural effects of motor control adaptions in LBP. We conclude that back pain-induced disrupted or reduced proprioceptive signaling likely plays a pivotal role in driving long-term changes in the top-down control of the motor system via motor and sensory cortical reorganization. In the outlook of this review, we explore whether motor control adaptations are also important for other (musculoskeletal) pain conditions.<\/jats:p>","DOI":"10.1177\/1073858418809074","type":"journal-article","created":{"date-parts":[[2018,11,2]],"date-time":"2018-11-02T10:26:38Z","timestamp":1541154398000},"page":"583-596","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":166,"title":["Low Back Pain: The Potential Contribution of Supraspinal Motor Control and Proprioception"],"prefix":"10.1177","volume":"25","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6004-8338","authenticated-orcid":false,"given":"Michael Lukas","family":"Meier","sequence":"first","affiliation":[{"name":"Integrative Spinal Research, Department of Chiropractic Medicine, University Hospital Balgrist, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrea","family":"Vrana","sequence":"additional","affiliation":[{"name":"Integrative Spinal Research, Department of Chiropractic Medicine, University Hospital Balgrist, Zurich, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Petra","family":"Schweinhardt","sequence":"additional","affiliation":[{"name":"Integrative Spinal Research, Department of Chiropractic Medicine, University Hospital Balgrist, Zurich, Switzerland"},{"name":"Alan Edwards Center for Research on Pain, McGill University, Montreal, Quebec, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2018,11,2]]},"reference":[{"key":"bibr1-1073858418809074","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00207.2018"},{"key":"bibr2-1073858418809074","doi-asserted-by":"publisher","DOI":"10.1007\/s00421-014-2985-8"},{"key":"bibr3-1073858418809074","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000231761.73859.2c"},{"key":"bibr4-1073858418809074","doi-asserted-by":"crossref","unstructured":"Adams RA, Shipp S, Friston KJ. 2013. 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