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Since then, knowledge about Parkinson\u2019s disease has been improved, and its pathophysiology, diagnosis, and treatments are well described in the scientific and medical literature. However, there is no way to prevent the disease from its progressive nature yet and only its symptoms can be minimized. It is known that the process of neurodegeneration begins before the onset of motor signs and symptoms of the disease, when diagnosis is usually made. Therefore, recognizing manifested non-motor symptoms can make an early diagnosis possible and lead to a better understanding of the disease. Autonomic dysfunctions are important non-motor manifestations of Parkinson\u2019s disease and affect the majority of patients. Importantly, heart failure is the third leading cause of death in people suffering from Parkinson\u2019s disease. Several evidences have shown the correlation between Parkinson\u2019s disease and the preexistence of cardiovascular diseases. Therefore, cardiovascular monitoring and identification of its dysfunctions can have a prodromal role for Parkinson\u2019s disease. This review presents studies of the literature that can lead to a better understanding of Parkinson\u2019s disease with special attention to its relation to heart and cardiovascular parameters.<\/jats:p>","DOI":"10.1177\/1073858421990000","type":"journal-article","created":{"date-parts":[[2021,2,15]],"date-time":"2021-02-15T04:48:12Z","timestamp":1613364492000},"page":"530-542","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":30,"title":["Heart Matters: Cardiac Dysfunction and Other Autonomic Changes in Parkinson\u2019s Disease"],"prefix":"10.1177","volume":"28","author":[{"given":"Valeria C.","family":"Gon\u00e7alves","sequence":"first","affiliation":[{"name":"Clinical & Experimental Neuroscience (NiCE), Biomedical Research Institute of Murcia (IMIB- Arrixaca), Murcia, Spain"},{"name":"Clinical & Experimental Neuroscience (NiCE), Institute for Ageing Research (IUIE), School of Medicine, Campus Mare Nostrum. 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