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The patient died from refractory disease despite therapy with protamine, initiation of chemotherapy, and supportive measures. The case illustrates the clinical presentation and diagnosis of heparin-like anticoagulants. Etiology, pathophysiology, and therapeutic options are discussed.<\/jats:p>","DOI":"10.1177\/1076029607309173","type":"journal-article","created":{"date-parts":[[2007,12,26]],"date-time":"2007-12-26T20:34:42Z","timestamp":1198701282000},"page":"360-364","source":"Crossref","is-referenced-by-count":30,"title":["Fatal Bleeding Due to a Heparin-Like Anticoagulant in a 37-Year-Old Woman Suffering From Systemic Mastocytosis"],"prefix":"10.1177","volume":"14","author":[{"given":"Christoph","family":"Sucker","sequence":"first","affiliation":[{"name":"Departments of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georg","family":"Mansmann","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Pneumology and Angiology, Heinrich Heine University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Steiner","sequence":"additional","affiliation":[{"name":"Department of Endocrinology, Diabetes and Rheumatology, Heinrich Heine University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Norbert","family":"Gattermann","sequence":"additional","affiliation":[{"name":"Hematology, Oncology and Clinical Immunology Heinrich Heine University Medical Center, D\u00fcsseldorf"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anette","family":"Schmitt-Graeff","sequence":"additional","affiliation":[{"name":"Department of Pathology, University of Freiburg Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Loncar","sequence":"additional","affiliation":[{"name":"Departments of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rudiger E.","family":"Scharf","sequence":"additional","affiliation":[{"name":"Departments of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marcus","family":"Stockschlader","sequence":"additional","affiliation":[{"name":"Departments of Hemostasis and Transfusion Medicine, Heinrich Heine University Medical Center, -duesseldorf.de"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,6,19]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2133.2001.04123.x"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1007\/s002920000439"},{"key":"atypb3","unstructured":"Valent P., Horny HP, Li C., et al. 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