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Anabolic-androgenic steroids have been reported to have anticoagulatory and profibrinolytic effects in patients with protein C deficiency. Despite these antithrombotic effects, the patient developed repeated venous thromboembolism during treatment with low-molecular-weight heparin. The net effect of anabolic-androgenic steroids on the haemostatic system may change from antithrombotic to prothrombotic in male abusers of anabolic steroids with protein C deficiency.<\/jats:p>","DOI":"10.1177\/1076029608324930","type":"journal-article","created":{"date-parts":[[2008,10,31]],"date-time":"2008-10-31T20:24:38Z","timestamp":1225484678000},"page":"228-231","source":"Crossref","is-referenced-by-count":10,"title":["Pulmonary Embolism Associated With Protein C Deficiency and Abuse of Anabolic-androgen Steroids"],"prefix":"10.1177","volume":"16","author":[{"given":"Alaa","family":"Alhadad","sequence":"first","affiliation":[{"name":"University of Lund, Vascular Center Malm\u00f6-Lund, Malm\u00f6 University Hospital, Malm\u00f6, Sweden,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Acosta","sequence":"additional","affiliation":[{"name":"University of Lund, Vascular Center Malm\u00f6-Lund, Malm\u00f6 University Hospital, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Latif","family":"Sarabi","sequence":"additional","affiliation":[{"name":"University of Lund, Vascular Center Malm\u00f6-Lund, Malm\u00f6 University Hospital, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tilo","family":"K\u00f6lbel","sequence":"additional","affiliation":[{"name":"University of Lund, Vascular Center Malm\u00f6-Lund, Malm\u00f6 University Hospital, Malm\u00f6, Sweden"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2008,10,30]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1249\/00005768-199509000-00004"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.2830490405"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(01)00448-8"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1177\/000331978603701005"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-4-22"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410120613"},{"key":"atypb7","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.1.212"},{"key":"atypb8","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(84)90165-8"},{"key":"atypb9","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1007\/BF02906308","volume":"14","author":"Mannucci PM","year":"1984","journal-title":"Ric Clin Lab"},{"key":"atypb10","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-3848(97)00163-1"},{"key":"atypb11","first-page":"971","volume":"106","author":"Bielawiec M.","year":"1979","journal-title":"Folia Haematol int Mag Klin Morphol Blutforsch"},{"key":"atypb12","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejim.2007.03.016"},{"key":"atypb13","first-page":"111","volume":"7","author":"Sanchez-Medal L.","year":"1971","journal-title":"Prog Hematol"},{"key":"atypb14","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196105112641901"},{"key":"atypb15","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(93)90014-Z"},{"key":"atypb16","doi-asserted-by":"publisher","DOI":"10.1159\/000073592"},{"key":"atypb17","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-5122(96)82004-4"}],"container-title":["Clinical and Applied Thrombosis\/Hemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1076029608324930","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1076029608324930","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:00:17Z","timestamp":1777384817000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1076029608324930"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10,30]]},"references-count":17,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,4]]}},"alternative-id":["10.1177\/1076029608324930"],"URL":"https:\/\/doi.org\/10.1177\/1076029608324930","relation":{},"ISSN":["1076-0296","1938-2723"],"issn-type":[{"value":"1076-0296","type":"print"},{"value":"1938-2723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,10,30]]}}}