{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:09:10Z","timestamp":1777478950339,"version":"3.51.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,3,6]],"date-time":"2012-03-06T00:00:00Z","timestamp":1330992000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:p>The aim of this study was to assess the baseline platelet hyperactivity in patients with acute coronary syndrome (ACS) and correlate it with the disease severity and clinical outcome.<\/jats:p>\n                  <jats:sec>\n                    <jats:title>Participants and Methods:<\/jats:title>\n                    <jats:p>This study was conducted on 60 patients with the first attack of non-ST-segment elevation ACS and 30 healthy controls. Patients were subdivided into 2 groups: group I: 40 patients with non-ST-segment elevation myocardial infarction (NSTEMI) and group II: 20 patients with unstable angina. All the studied patients were subjected to baseline platelet function analysis using platelet function analyzer 100 (PFA-100).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Group I patients showed significantly lower PFA-100 closure time (CT) than group II ( P = .04) and control group ( P = .03). The occurrence of complications in NSTEMI patients was associated with older age, hypertension, and shorter baseline collagen adenosine diphosphate PFA-100 CT ( P &lt; .05).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>NSTEMI patients proved to have enhanced platelet function that can be used as a predictor of the outcome.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1076029612439341","type":"journal-article","created":{"date-parts":[[2012,3,7]],"date-time":"2012-03-07T20:25:11Z","timestamp":1331151911000},"page":"256-260","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Clinical Significance of Baseline Platelet Reactivity in Patients With Acute Coronary Syndrome"],"prefix":"10.1177","volume":"19","author":[{"given":"Hebatallah A.","family":"Sedky","sequence":"first","affiliation":[{"name":"Department of Clinical Pathology, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dahlia A.","family":"El-Sewefy","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abeer A.","family":"Saad","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed I.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Heba M. A.","family":"El-Maraghy","sequence":"additional","affiliation":[{"name":"Department of Clinical Pathology, Ain Shams University, Cairo, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2012,3,6]]},"reference":[{"key":"bibr1-1076029612439341","unstructured":"World Health Organization. Cardiovascular diseases (CVDs) Fact Sheet N\u00b0317, September 2011. www.who.int\/mediacentre\/factsheets\/fs317\/en\/index.html"},{"key":"bibr2-1076029612439341","unstructured":"World Health Organization. Mortality Country Fact Sheet 2006. www.who.int\/whosis\/mort\/profiles\/mort_emro_egy_egypt.pdf. 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