{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:12:17Z","timestamp":1777479137631,"version":"3.51.4"},"reference-count":27,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2013,3,20]],"date-time":"2013-03-20T00:00:00Z","timestamp":1363737600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:p>Patients with iliac deep vein thrombosis (DVT) have a poor prognosis and high incidence of postthrombotic syndrome (PTS). We evaluated the effect of low-molecular-weight heparin (LMWH; tinzaparin) versus usual care (tinzaparin plus warfarin for \u226512 weeks at home) in the development of PTS according to DVT location (iliac\/noniliac) by retrospective analysis of the Home-LITE cohort (480 patients with proximal DVT). Patients with iliac DVT had an overall odds ratio of 0.53 (95% confidence interval [CI] 0.33, 0.83; P = .0079) for PTS (including ulcer data) in favor of tinzaparin. Patients with noniliac DVT had a similar odds ratio (0.79 [95% CI 0.67, 0.93], P = .0046) to that reported in the overall Home-LITE population (0.76 [95% CI 0.66, 0.89], P = .0004; including ulcer data), both in favor of tinzaparin. Long-term LMWH may be a suitable alternative for the prevention of PTS in patients with iliac DVT who are unlikely to undergo invasive thrombolysis.<\/jats:p>","DOI":"10.1177\/1076029613481845","type":"journal-article","created":{"date-parts":[[2013,3,21]],"date-time":"2013-03-21T20:48:49Z","timestamp":1363898929000},"page":"476-481","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Effect of Long-Term LMWH on Post-thrombotic Syndrome in Patients With Iliac\/Noniliac Venous Thrombosis"],"prefix":"10.1177","volume":"19","author":[{"given":"Russell D.","family":"Hull","sequence":"first","affiliation":[{"name":"University of Calgary, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jane","family":"Liang","sequence":"additional","affiliation":[{"name":"University of Calgary, Calgary, Alberta, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tazmin","family":"Merali","sequence":"additional","affiliation":[{"name":"Drug Intelligence, Toronto, Ontario, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2013,3,20]]},"reference":[{"key":"bibr1-1076029613481845","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-149-10-200811180-00004"},{"key":"bibr2-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2011.03.008"},{"key":"bibr3-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9343(01)00661-1"},{"key":"bibr4-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2301"},{"key":"bibr5-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2005.01216.x"},{"key":"bibr6-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1177\/1531003509359311"},{"key":"bibr7-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2009.03464.x"},{"key":"bibr8-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1067\/mva.2000.105664"},{"key":"bibr9-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2008.12.023"},{"key":"bibr10-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1177\/1076029612443306"},{"key":"bibr11-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1016\/0741-5214(93)90325-G"},{"key":"bibr12-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-01-131656"},{"key":"bibr13-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2006.02.022"},{"key":"bibr14-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199603143341101"},{"key":"bibr15-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199603143341102"},{"key":"bibr16-1076029613481845","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-153-1-201007060-00012"},{"key":"bibr17-1076029613481845","doi-asserted-by":"publisher","DOI":"10.1097\/01.RVI.0000203802.35689.66"},{"issue":"4","key":"bibr18-1076029613481845","first-page":"292","volume":"29","author":"Broholm 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