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A series of 206 patients diagnosed with lower extremity venous thrombosis were retrospectively reviewed. The PTS was observed in 30.58% of the patients. Recurrent venous thrombosis was identified in 3.4% of the patients without PTS and in 33.3% of patients with PTS ( P &lt; .001). Inherited thrombophilia alone or in association with recurrent venous thrombosis was more commonly detected when PTS was moderate to severe ( P = .04 and &lt;.001) or severe ( P &lt; .001). Recurrent venous thrombosis increases the incidence of PTS significantly. The severity of PTS raises when an underlying thrombophilia is present either alone or in association with recurrent venous thrombosis.<\/jats:p>","DOI":"10.1177\/1076029613497423","type":"journal-article","created":{"date-parts":[[2013,7,27]],"date-time":"2013-07-27T02:22:03Z","timestamp":1374891723000},"page":"87-90","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Contribution of Recurrent Venous Thrombosis and Inherited Thrombophilia to the Pathogenesis of Postthrombotic Syndrome"],"prefix":"10.1177","volume":"21","author":[{"given":"Raghid","family":"Kreidy","sequence":"first","affiliation":[{"name":"Department of Vascular Surgery, University of Balamand, Beirut, 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