{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:15:51Z","timestamp":1777479351430,"version":"3.51.4"},"reference-count":24,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2014,8,21]],"date-time":"2014-08-21T00:00:00Z","timestamp":1408579200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>Recent studies suggest that the soluble triggering receptor expressed on myeloid cells-like transcript 1 (sTLT-1) facilitate atherothrombosis. Therefore, we evaluated sTLT-1 as a functional measure of atherothrombosis in acute coronary syndrome (ACS).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>Levels of sTLT-1 were determined by enzyme-linked immunosorbent assay on plasma from patients with potential ACS and compared with an age-matched control group with similar risk factors for cardiovascular disease.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of 53 patients enrolled, 19 patients were undergoing ACS (15 unstable angina, 2 non\u2013ST-segment elevated myocardial infarction, and 2 ST-segment elevated myocardial infarction), 5 patients were found with noncardiac chest pain, and 29 were in the control group. The mean plasma sTLT-1 values in the ACS group were 4.644 ng\/mL \u00b1 1.277 standard error of the mean (SEM), in the noncardiac chest pain group were 0.708 ng\/mL \u00b1 0.427 SEM, and in the control group were 1.007 ng\/mL \u00b1 0.098 SEM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>A statistically significant difference exists between patients experiencing cardiogenic chest pain versus controls ( P &lt; .05), suggesting sTLT-1 as a potential tool for understanding atherothrombosis in ACS.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1076029614547298","type":"journal-article","created":{"date-parts":[[2014,8,22]],"date-time":"2014-08-22T01:59:36Z","timestamp":1408672776000},"page":"30-34","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":13,"title":["Levels of Soluble TREM-Like Transcript 1 in Patients Presenting to the Emergency Department With Chest Pain"],"prefix":"10.1177","volume":"21","author":[{"given":"Omar L.","family":"Esponda","sequence":"first","affiliation":[{"name":"Department of Internal Medicine, Hospital Universitario Dr Ram\u00f3n Ruiz Arnau, Universidad Central del Caribe, Bayam\u00f3n, PR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Hunter","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital Universitario Dr Ram\u00f3n Ruiz Arnau, Universidad Central del Caribe, Bayam\u00f3n, PR, USA"},{"name":"Laboratory of Anatomy and Cell Biology, Hospital HIMA San Pablo, Bayam\u00f3n, PR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 R. Rivera Del","family":"R\u00edo","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Hospital Universitario Dr Ram\u00f3n Ruiz Arnau, Universidad Central del Caribe, Bayam\u00f3n, PR, USA"},{"name":"Laboratory of Anatomy and Cell Biology, Hospital HIMA San Pablo, Bayam\u00f3n, PR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. Valance","family":"Washington","sequence":"additional","affiliation":[{"name":"Department of Biology, University of Puerto Rico-Rio Piedras, San Juan, PR, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2014,8,21]]},"reference":[{"key":"bibr1-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1038\/35025203"},{"issue":"5","key":"bibr2-1076029614547298","doi-asserted-by":"crossref","first-page":"1307S","DOI":"10.1093\/ajcn\/72.5.1307s","volume":"72","author":"McGill HC","year":"2000","journal-title":"Am J Clin Nutr"},{"issue":"1","key":"bibr3-1076029614547298","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1161\/01.RES.0000252802.25497.b7","volume":"100","author":"von HP","year":"2007","journal-title":"Circ Res"},{"key":"bibr4-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0708400"},{"key":"bibr5-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2009.04.001"},{"key":"bibr6-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1172\/JCI36175"},{"key":"bibr7-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-01-0315"},{"key":"bibr8-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M600489200"},{"key":"bibr9-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e3283358116"},{"key":"bibr10-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1038\/nm810"},{"key":"bibr11-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000028590.02477.6F"},{"issue":"7","key":"bibr12-1076029614547298","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1016\/j.jacc.2007.02.013","volume":"50","author":"Anderson JL","year":"2007","journal-title":"J Am Coll Cardiol"},{"key":"bibr13-1076029614547298","first-page":"IV","volume":"112","year":"2005","journal-title":"Circulation"},{"key":"bibr14-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1007\/s00380-009-1199-1"},{"key":"bibr15-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2009.06.004"},{"key":"bibr16-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1159\/000006940"},{"key":"bibr17-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2009.03.076"},{"key":"bibr18-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1177\/0003319709356785"},{"key":"bibr19-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1016\/j.cccn.2004.01.012"},{"key":"bibr20-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1016\/S0167-5273(98)00075-8"},{"key":"bibr21-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1080\/10245330500072405"},{"issue":"1","key":"bibr22-1076029614547298","first-page":"83","volume":"10","author":"Draz N","year":"2003","journal-title":"Egypt J Immunol"},{"key":"bibr23-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-010-0213-5"},{"key":"bibr24-1076029614547298","doi-asserted-by":"publisher","DOI":"10.1177\/1076029609344981"}],"container-title":["Clinical and Applied Thrombosis\/Hemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1076029614547298","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1076029614547298","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1076029614547298","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:05:31Z","timestamp":1777385131000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1076029614547298"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,8,21]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2015,1]]}},"alternative-id":["10.1177\/1076029614547298"],"URL":"https:\/\/doi.org\/10.1177\/1076029614547298","relation":{},"ISSN":["1076-0296","1938-2723"],"issn-type":[{"value":"1076-0296","type":"print"},{"value":"1938-2723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,8,21]]}}}