{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T15:24:32Z","timestamp":1780759472995,"version":"3.54.1"},"reference-count":23,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T00:00:00Z","timestamp":1422489600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2016,7]]},"abstract":"<jats:sec>\n                    <jats:title>Background\/Aim:<\/jats:title>\n                    <jats:p>To evaluate the value of d-dimer, P-selectin, and platelet count in patients with cirrhotic portal hypertension (PHT) for prediction of portal vein thrombosis (PVT) after devascularization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A total of 137 patients with cirrhotic PHT who undergone devascularization from January 2012 to April 2014 were retrospectively reviewed, all of them were divided into 2 groups (PVT group and non-PVT group) by Doppler ultrasonography (DU) examination. The level of d-dimer, P-selectin, and platelet count was tested during the perioperative period.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>In all, 38 (27.7%) patients were found to have PVT by DU examination postoperatively. In contrast to the non-PVT group, the level of d-dimer, P-selectin, and platelet count in the PVT group was much higher significantly at 1, 3, and 7 days after devascularization. ( P &lt; .05). However, in the 15 days after surgery, the difference in P-selectin between the 2 groups was not significant ( P = .260). It was shown that the highest sensitivity of the 3 markers for PVT was d-dimer, the highest specificity belonged to P-selectin. The area under receiver\u2013operating characteristic (ROC) curve of P-selectin was the biggest of the 3 markers. When the 3 markers were combined to be used to diagnose PVT, the sensitivity was increased to 0.907, with a slight drop of specificity to 0.693, the area under the ROC curve was 0.927.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The level of d-dimer, P-selectin, and platelet count might be good candidate predictive markers for PVT in patients with cirrhotic PHT after devascularization. The combined test of the 3 markers can increase the value of prediction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1076029615569273","type":"journal-article","created":{"date-parts":[[2015,1,29]],"date-time":"2015-01-29T23:12:24Z","timestamp":1422573144000},"page":"471-475","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Evaluation of the Value of\n                    <scp>d<\/scp>\n                    -Dimer, P-Selectin, and Platelet Count for Prediction of Portal Vein Thrombosis After Devascularization"],"prefix":"10.1177","volume":"22","author":[{"given":"Yang","family":"Fei","sequence":"first","affiliation":[{"name":"Department of General Surgery, the 81st Hospital of P.L.A., P.L.A. Cancer Center, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-quan","family":"Zong","sequence":"additional","affiliation":[{"name":"Department of General Surgery, the 81st Hospital of P.L.A., P.L.A. Cancer Center, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of General Surgery, the 81st Hospital of P.L.A., P.L.A. Cancer Center, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ren-min","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of General Surgery, the 81st Hospital of P.L.A., P.L.A. Cancer Center, Nanjing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2015,1,29]]},"reference":[{"key":"bibr1-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(02)01095-4"},{"key":"bibr2-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.02301.x"},{"key":"bibr3-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2005.05.009"},{"key":"bibr4-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510280339"},{"key":"bibr5-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22273"},{"key":"bibr6-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2008.03267.x"},{"key":"bibr7-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2011.12.015"},{"key":"bibr8-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.108.175679"},{"key":"bibr9-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2011.160"},{"key":"bibr10-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2011.05.097"},{"key":"bibr11-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2014.05.065"},{"issue":"4","key":"bibr12-1076029615569273","first-page":"291","volume":"16","author":"Zong GQ","year":"2014","journal-title":"Med Ultrason"},{"key":"bibr13-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2002.05527.x"},{"key":"bibr14-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2000.01514.x"},{"key":"bibr15-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2014.08.003"},{"key":"bibr16-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0609.2001.00359.x"},{"key":"bibr17-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/j.bios.2010.06.048"},{"key":"bibr18-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/j.cccn.2004.03.008"},{"key":"bibr19-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa054444"},{"key":"bibr20-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-08-237354"},{"key":"bibr21-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1177\/1076029611405032"},{"key":"bibr22-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2141.2000.01813.x"},{"key":"bibr23-1076029615569273","doi-asserted-by":"publisher","DOI":"10.1016\/S0741-5214(03)01033-4"}],"container-title":["Clinical and Applied Thrombosis\/Hemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1076029615569273","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/1076029615569273","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/1076029615569273","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:05:40Z","timestamp":1777385140000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/1076029615569273"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,1,29]]},"references-count":23,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2016,7]]}},"alternative-id":["10.1177\/1076029615569273"],"URL":"https:\/\/doi.org\/10.1177\/1076029615569273","relation":{},"ISSN":["1076-0296","1938-2723"],"issn-type":[{"value":"1076-0296","type":"print"},{"value":"1938-2723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,1,29]]}}}