{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T04:58:16Z","timestamp":1791694696352,"version":"4.3.4"},"reference-count":38,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2015,10,22]],"date-time":"2015-10-22T00:00:00Z","timestamp":1445472000000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:sec>\n                    <jats:title>Background:<\/jats:title>\n                    <jats:p>The impact of fat distribution, muscle mass, and muscle strength on no-reflow and severity of coronary artery disease in patients with ST-segment elevation myocardial infarction (STEMI) remains unclear.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To investigate association between muscle strength and fat and muscle mass and severity of coronary atherosclerosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We included 218 patients with STEMI who had undergone primary percutaneous coronary intervention. We evaluated the no-reflow phenomenon in infarct-related artery and calculated Gensini scores from initial angiograms as indicative of coronary atherosclerosis severity. The patients were divided into 2 groups as patients with no-reflow and with thrombolysis in myocardial infarction grade 3 flow and patients with low (&lt;55) Gensini and with high (\u226555) Gensini. Patients\u2019 total fat, muscle mass, visceral fat mass, and muscle strength were measured via body composition analyzer and handgrip dynamometer.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>High Gensini patients had a greater body mass index (BMI) and lower handgrip strength and more visceral fat ( P = .05, P = .017, and P &lt; .001, respectively). The patients with no-reflow had significantly lower handgrip strength and more visceral fat (both, P &lt; .001). In multivariate regression analysis, visceral fat and handgrip strength were associated with high no-reflow rate and high Gensini scores in patients with STEMI ( P = .001, P = .014, P = .022, and P = .010; respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Increased visceral fat and lower handgrip strength may be related to increased no-reflow rate and coronary plaque burden in STEMI. Visceral fat and muscle strength may be better prognostic markers than weight, BMI, total fat, and muscle mass in coronary artery disease.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/1076029615613159","type":"journal-article","created":{"date-parts":[[2015,10,22]],"date-time":"2015-10-22T20:59:55Z","timestamp":1445547595000},"page":"367-373","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Lower Muscle Strength and Increased Visceral Fat Associated With No-reflow and High Gensini Score in STEMI"],"prefix":"10.1177","volume":"23","author":[{"given":"Burak","family":"Ay\u00e7a","sequence":"first","affiliation":[{"name":"Department of Cardiology, Ba\u011fc\u0131lar Education and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Didem","family":"Kafadar","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ba\u011fc\u0131lar Education and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Avsar","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ba\u011fc\u0131lar Education and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130. \u0130lker","family":"Avci","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ba\u011fc\u0131lar Education and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatih","family":"Ak\u0131n","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Mu\u011fla S\u0131tk\u0131 Ko\u00e7man University, Medical School, Mu\u011fla, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ertugrul","family":"Okuyan","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ba\u011fc\u0131lar Education and Research Hospital, Istanbul, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M. Hakan","family":"Dinckal","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Ba\u011fc\u0131lar Education and Research Hospital, Istanbul, 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