{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T15:15:55Z","timestamp":1787498155967,"version":"build-2736575974"},"reference-count":40,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2020,1,1]],"date-time":"2020-01-01T00:00:00Z","timestamp":1577836800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005068","name":"Jimma University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005068","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2020,1,1]]},"abstract":"<jats:p>Deep venous thrombosis (DVT) is a common clinical problem associated with substantial morbidity and mortality. Knowledge of the global burden of DVT recurrence is deficient in Africa, including Ethiopia. The objective of the study was to assess deep venous thrombosis recurrence and its predictors at selected tertiary hospitals in Ethiopia. Prospective cohort study was conducted among hospitalized DVT patients. Data were analyzed using SPSS version 21.0. To identify the independent predictors of DVT-recurrence, multiple stepwise-backward Cox-regression analysis was done. Statistical significance was considered at P value &lt; .05. A total of 129 participants were included (65.1% females) with mean \u00b1 SD age of 38.63 \u00b1 17.67 years. About 26.4% of patients developed recurrent venous thromboembolism. Pulmonary embolism accounted for 17.60% of recurrent event. The overall incidence density of DVT recurrence was 2.99 per 1000 person-days. The mean \u00b1 SD survival time to DVT recurrence was 42.03 \u00b1 22.371 days. Age \u2265 50 years (adjusted hazard ratio [AHR]: 5.566; 95% CI: 1.587-19.518; P = .007), occasional alcohol consumption (AHR: 2.011; 95% CI: 1.307-6.314; P = .019), surgical history (AHR: 6.218; 95% CI: 1.540-25.104; P = .010), pregnancy (AHR: 2.0911; 95% CI: 1.046-4.179; P = .037), diabetes mellitus (AHR: 8.048; 95% CI: 2.494-25.966; P &lt; .001), unmet activated partial thromboplastin time target after 24 hours of heparin (AHR: 1.129; 95% CI: 0.120-10.600; P = .011), proximal site involvement (AHR: 5.937; 95% CI: 1.300-27.110; P = .022), and previous history of DVT (AHR: 2.48; 95% CI: 1.085-11.20; P = .0002) were independent predictors of DVT recurrence. The DVT recurrence rate was high in the study area, which is even complicated with pulmonary embolism as well as death. Efforts are needed to prevent and reduce the development of DVT recurrence.<\/jats:p>","DOI":"10.1177\/1076029620941077","type":"journal-article","created":{"date-parts":[[2020,9,15]],"date-time":"2020-09-15T14:20:45Z","timestamp":1600179645000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":19,"title":["Deep Venous Thrombosis Recurrence and Its Predictors at Selected Tertiary Hospitals in Ethiopia: A Prospective Cohort Study"],"prefix":"10.1177","volume":"26","author":[{"given":"Abera","family":"Mulatu","sequence":"first","affiliation":[{"name":"Amanuel Mental Specialized Hospital, Finfinnee, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8373-5309","authenticated-orcid":false,"given":"Tsegaye","family":"Melaku","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Legese","family":"Chelkeba","sequence":"additional","affiliation":[{"name":"School of Pharmacy, Institute of Health, Jimma University, Jimma, Ethiopia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,9,15]]},"reference":[{"key":"bibr1-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61904-1"},{"key":"bibr2-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-0656"},{"key":"bibr3-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2008.08.018"},{"key":"bibr4-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1016\/0049-3848(95)00204-9"},{"key":"bibr5-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-009-0378-3"},{"key":"bibr6-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.93.12.2212"},{"key":"bibr7-1076029620941077","first-page":"2012","volume":"391734","author":"Palareti G","year":"2012","journal-title":"Scientifica"},{"key":"bibr8-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.l4363"},{"key":"bibr9-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-01-0108"},{"issue":"1","key":"bibr10-1076029620941077","first-page":"85","volume":"5","author":"Gader AA","year":"2009","journal-title":"Vasc Health Risk Manag"},{"key":"bibr11-1076029620941077","doi-asserted-by":"publisher","DOI":"10.1186\/s12959-015-0065-x"},{"issue":"12","key":"bibr12-1076029620941077","first-page":"394","volume":"92","author":"Conklin P","year":"2009","journal-title":"R I Med J"},{"key":"bibr13-1076029620941077","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2015.76.2.72"},{"issue":"7","key":"bibr14-1076029620941077","first-page":"432","volume":"75","author":"Gebremedhin A","year":"1998","journal-title":"East Afr Med J"},{"issue":"2","key":"bibr15-1076029620941077","first-page":"61","volume":"18","author":"Haile L","year":"2013","journal-title":"East Central African J Surg"},{"key":"bibr16-1076029620941077","unstructured":"Food M, Administration HC, Ethiopia CAo. 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