{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,13]],"date-time":"2026-05-13T02:12:40Z","timestamp":1778638360608,"version":"3.51.4"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2021,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Since the beginning of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) pandemic, there have been many reports of increased incidence of venous thromboembolism and arterial events as a complication.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To determine the incidence of symptomatic thrombotic events (TEs) in patients hospitalized for SARS-CoV2 disease (coronavirus 19 [Covid-19]).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective single-center cohort study with adult patients with a positive reverse transcriptase-polymerase chain reaction (rt-PCR) for SARS-CoV2, included from the date of diagnosis of Covid-19 and followed for 90 days or until death.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      A total of 1621 patients were included in this study. The median age was 73 years (interquartile range\n                      <jats:sub>25th-75th<\/jats:sub>\n                      [IQR] 53-87 years) and 57% (913) were female. Overall mortality was 21.6% (348). The overall incidence of symptomatic TEs within 90 days of diagnosis was 1.8% (30 of 1621) occurring in 28 patients, including an incidence of pulmonary embolism of 0.9% (15, 95% confidence interval [CI] 0.60%-1.6%), deep venous thrombosis of 0.61% (10, 95% CI 0.2%-1%), ischemic stroke of 0.25% (4, 95% CI 0.09%-0.65%), and ischemic arterial events of 0.06% (1, 95% CI 0.008%-0.43%). No acute coronary syndrome events were recorded. The incidence of symptomatic TEs was significantly lower in the general ward than in intensive care units (1.2% vs 5.7%; p\u2009&lt;\u2009.001). The median time since positive rt-PCR for SARS-CoV2 to symptomatic TE was 22.5 days (IQR 19-43 days). There was no significant difference in the proportion of patients receiving (53.6%) and not receiving thromboprophylaxis (66.5%) and the development of TEs.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>The overall incidence of symptomatic TEs among these patients was lower than the incidence previously reported.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10760296211051712","type":"journal-article","created":{"date-parts":[[2021,10,29]],"date-time":"2021-10-29T08:47:58Z","timestamp":1635497278000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Low Incidence of Symptomatic Thrombotic Events in Adult Patients Hospitalized with Coronavirus 19: A Retrospective Cohort Study"],"prefix":"10.1177","volume":"27","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1331-8264","authenticated-orcid":false,"given":"Marcelo G.","family":"Vallone","sequence":"first","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carolina","family":"Vazquez","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"},{"name":"*Co-first authorship."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fernando A.","family":"Chuliber","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ver\u00f3nica","family":"Privitera","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Augusto","family":"Ferraris","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"},{"name":"University of Buenos Aires, Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramiro F.","family":"Cantarella","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda F.","family":"Indo","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diego M.","family":"Sanchez Thomas","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ver\u00f3nica A.","family":"Peuchot","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"},{"name":"Co-senior authorship."}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1480-5101","authenticated-orcid":false,"given":"Fernando J.","family":"Vazquez","sequence":"additional","affiliation":[{"name":"Hospital Italiano de Buenos Aires, Ciudad Aut\u00f3noma de Buenos Aires, Argentina"},{"name":"Co-senior authorship."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,10,29]]},"reference":[{"key":"bibr1-10760296211051712","unstructured":"Roser M, Ritchie H, Ortiz-Ospina E, et al. \u201cCoronavirus Pandemic (COVID-19)\u201d. 2020. 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