{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T05:20:54Z","timestamp":1787116854656,"version":"build-2736575974"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Novartis Pharmaceuticals, Iran"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>Data describing physicians\u2019 and patients\u2019 perspectives towards immune thrombocytopenia (ITP) management and impact of disease in Iran are limited. This ITP World Impact Survey was conducted between October 2019 and October 2020. Of the 114 patients included in the survey, 17 were aged \u226418 years. Forty-seven physicians, including 22 pediatric hematologists, participated in the survey. Fatigue and anxiety around stable platelet counts were frequent patient-reported symptoms at diagnosis and at survey completion. According to physicians, \u201cwatch-and-wait\u201d was the preferred treatment option for mean (standard deviation) proportion of 50.1 (24.1) and 48.6 (21.8) of their adult and pediatric patients, respectively, following first diagnosis. Per adult and pediatric hematologists, the most prescribed treatments for newly diagnosed patients based on available answers were steroids (100%, n\u2009=\u200920\/20; 89%, n\u2009=\u200916\/18), respectively. Forty percent of adult (n\u2009=\u200910\/25) and 38% of pediatric hematologists (n\u2009=\u20098\/21) reported that ITP reduced patients\u2019 quality of life. Energy levels (46%, n\u2009=\u200952\/112) and ability to concentrate on everyday activities (42%, n\u2009=\u200947\/113) were the most affected aspects of patients' lives. This I-WISh study in Iran underlined the negative impact of ITP on patients.<\/jats:p>","DOI":"10.1177\/10760296221130335","type":"journal-article","created":{"date-parts":[[2023,1,11]],"date-time":"2023-01-11T18:01:47Z","timestamp":1673460107000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Patient and Physician Perspectives in the Management of Immune Thrombocytopenia in Iran: Responses from the ITP World Impact Survey (I-WISh)"],"prefix":"10.1177","volume":"29","author":[{"given":"Peyman","family":"Eshghi","sequence":"first","affiliation":[{"name":"Pediatric Congenital Hematologic Disorders Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hassan","family":"Abolghasemi","sequence":"additional","affiliation":[{"name":"Pediatric Congenital Hematologic Disorders Research Center, Research Institute for Children's Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ali A.","family":"Akhlaghi","sequence":"additional","affiliation":[{"name":"Clinical Trial Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Farzaneh","family":"Ashrafi","sequence":"additional","affiliation":[{"name":"Internal Medicine Department, Isfahan University of Medical Sciences, Isfahan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammadreza","family":"Bordbar","sequence":"additional","affiliation":[{"name":"Hematology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abbas","family":"Hajifathali","sequence":"additional","affiliation":[{"name":"Hematopoietic Stem Cell Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2368-6749","authenticated-orcid":false,"given":"Hamed","family":"Hosseini","sequence":"additional","affiliation":[{"name":"Clinical Trial Center, Tehran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nargesbeigom","family":"Mirbehbahani","sequence":"additional","affiliation":[{"name":"Golestan University of Medical Sciences, Cancer Research Center, Gorgan, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayat","family":"Abedini","sequence":"additional","affiliation":[{"name":"Medical Department, Novartis Pharma Services AG, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Narges","family":"Shahsavarani","sequence":"additional","affiliation":[{"name":"Medical Department, Novartis Pharma Services AG, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Faranoush","sequence":"additional","affiliation":[{"name":"Pediatric Growth and Development Research Center, Iran University of Medical Sciences, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,1,11]]},"reference":[{"key":"bibr1-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2008-07-162503"},{"key":"bibr2-10760296221130335","volume-title":"ITP-Immune Thrombocytopenic Purpura","author":"Justiz Vaillant AA","year":"2022"},{"key":"bibr3-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1016\/j.hoc.2013.03.001"},{"key":"bibr4-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000812"},{"key":"bibr5-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019000966"},{"key":"bibr6-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0609.2007.00844.x"},{"key":"bibr7-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.24463"},{"key":"bibr8-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26045"},{"key":"bibr9-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.26036"},{"key":"bibr10-10760296221130335","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2230.1994.tb01167.x"},{"key":"bibr11-10760296221130335","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1111\/bjh.15145","volume":"181","author":"Grant L","year":"2018","journal-title":"Brit J 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