{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T04:12:48Z","timestamp":1789186368124,"version":"build-2803163510"},"reference-count":49,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Becton Dickinson and Company"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>We assessed the relationship between peripherally inserted central catheter (PICC) diameters and symptomatic deep vein thrombosis (DVT) rates. We conducted a systematic search for articles published between 2010 and 2021 reporting DVT incidence by catheter diameter in patients who had a PICC, followed by meta-analyses for DVT risk in each diameter group. Pooled DVT rates were incorporated into an economic model. Of 1627 abstracts screened, 47 studies were included. The primary meta-analysis of 40 studies demonstrated the incidence of DVT was 0.89%, 3.26%, 5.46%, and 10.66% for 3, 4, 5, and 6 French (Fr) PICCs ( P\u2009\u2009=\u2009\u2009.01 between 4 and 5 Fr). Rates of DVT were not significantly different between oncology and nononcology patients ( P\u2009\u2009=\u2009\u2009.065 for 4 Fr and P\u2009\u2009=\u2009\u2009.99 for 5 Fr). The DVT rate was 5.08% for ICU patients and 4.58% for non-ICU patients ( P\u2009\u2009=\u2009\u2009.65). The economic model demonstrated an annual, incremental cost savings of US$114 053 for every 5% absolute reduction in 6 Fr PICCs use. Using the smallest PICC that meets the patients\u2019 clinical needs may help to mitigate risks and confer savings.<\/jats:p>","DOI":"10.1177\/10760296221144041","type":"journal-article","created":{"date-parts":[[2023,6,27]],"date-time":"2023-06-27T07:54:25Z","timestamp":1687852465000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":28,"title":["Symptomatic Deep Vein Thrombosis Associated With Peripherally Inserted Central Catheters of Different Diameters: A Systematic Review and Meta-Analysis"],"prefix":"10.1177","volume":"29","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9495-1293","authenticated-orcid":false,"given":"Amit","family":"Bahl","sequence":"first","affiliation":[{"name":"Department of Emergency Medicine, Beaumont Hospital, Royal Oak, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8684-7100","authenticated-orcid":false,"given":"Kimberly","family":"Alsbrooks","sequence":"additional","affiliation":[{"name":"Medical Affairs, Becton Dickinson and Company, Franklin Lakes, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Smeet","family":"Gala","sequence":"additional","affiliation":[{"name":"Medical Affairs, Becton Dickinson and Company, Franklin Lakes, NJ, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus","family":"Hoerauf","sequence":"additional","affiliation":[{"name":"Medical Affairs, Becton Dickinson and Company, Franklin Lakes, NJ, USA"},{"name":"Department of Anesthesiology and Intensive Care, Medical University of Vienna, Wien, Austria"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,6,27]]},"reference":[{"key":"bibr1-10760296221144041","doi-asserted-by":"publisher","DOI":"10.1177\/1129729819852203"},{"key":"bibr2-10760296221144041","doi-asserted-by":"publisher","DOI":"10.1177\/2050312120929238"},{"key":"bibr3-10760296221144041","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/6043427"},{"key":"bibr4-10760296221144041","doi-asserted-by":"publisher","DOI":"10.7326\/M15-0744"},{"key":"bibr5-10760296221144041","doi-asserted-by":"publisher","DOI":"10.1177\/1129729820916113"},{"key":"bibr6-10760296221144041","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCOUTCOMES.119.005659"},{"key":"bibr7-10760296221144041","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-0923"},{"key":"bibr8-10760296221144041","doi-asserted-by":"publisher","DOI":"10.2147\/CEOR.S85635"},{"key":"bibr9-10760296221144041","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2014.11.024"},{"key":"bibr10-10760296221144041","unstructured":"Infusion Nurses Society. 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