{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:07:16Z","timestamp":1777478836078,"version":"3.51.4"},"reference-count":34,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T00:00:00Z","timestamp":1672531200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Star of Jiao-Tong University\u201d Medical-Industry Interdisciplinary Research Fund","award":["02.101004.282.022"],"award-info":[{"award-number":["02.101004.282.022"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2023,1]]},"abstract":"<jats:p>As one of the frequent complications leading to poor prognosis in hospitalized COVID-19 patients, a better understanding of venous thromboembolism (VTE) in COVID-19 patients is needed. We conducted a single-center, retrospective study on 96 COVID-19 patients admitted to the intensive care unit (ICU) from April to June 2022, in Shanghai Renji Hospital. Records of these COVID-19 patients upon admission were reviewed for demographic information, co-morbidities, vaccinations, treatment, and laboratory tests. VTE occurred in 11 (11.5%) cases among 96 COVID-19 patients despite the standard thromboprophylaxis since ICU admission. In COVID-VTE patients, a significant increase in B cells and a decrease in Ts cells were observed and a strong negative correlation ( r\u2009=\u2009\u22120.9524, P\u2009=\u2009.0003) was found between these two populations. In COVID-19 patients with VTE, increased MPV and decreased albumin levels were seen in addition to the common VTE indicators of D-dimer abnormalities. The altered lymphocyte composition in COVID-VTE patients is noteworthy. In addition to D-dimer, MPV and albumin levels might be novel indicators for the risk of VTE in COVID-19 patients.<\/jats:p>","DOI":"10.1177\/10760296231177676","type":"journal-article","created":{"date-parts":[[2023,5,25]],"date-time":"2023-05-25T16:17:57Z","timestamp":1685031477000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Lymphocytes, Mean Platelet Volume, and Albumin in Critically Ill COVID-19 Patients  with Venous Thromboembolism"],"prefix":"10.1177","volume":"29","author":[{"given":"Rundan","family":"Duan","sequence":"first","affiliation":[{"name":"Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qihong","family":"Ni","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yinan","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mingli","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Critical Care Medicine, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peng","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kai","family":"Yuan","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Philipp","family":"von Hundelshausen","sequence":"additional","affiliation":[{"name":"Institute for Cardiovascular Prevention (IPEK), Ludwig-Maximilians-University, Munich, Germany"},{"name":"German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingpu","family":"Zhu","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-1303-0345","authenticated-orcid":false,"given":"Lei","family":"Lv","sequence":"additional","affiliation":[{"name":"Department of Vascular Surgery, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,5,25]]},"reference":[{"key":"bibr1-10760296231177676","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)00838-8"},{"key":"bibr2-10760296231177676","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2020.08.020"},{"key":"bibr3-10760296231177676","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019003603"},{"key":"bibr4-10760296231177676","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24043169"},{"key":"bibr5-10760296231177676","unstructured":"Karagoz I, Aktas G, Yoldas H, et al. 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