{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T07:35:16Z","timestamp":1785569716292,"version":"3.56.0"},"reference-count":27,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:p>\n                    Venous thromboembolism (VTE) is a leading cause of maternal mortality. Obesity and cesarean delivery are established risk factors for pregnancy-related VTE. We identified additional risk factors among patients with obesity who underwent a cesarean delivery to identify those who need VTE prophylaxis. We conducted a secondary analysis of data from the Maternal-Fetal Medicine Units Network (MFMU) Cesarean Registry Database using a case-control design. Cases were identified as women with obesity having a pre-pregnancy body mass index of &gt;30\u2005kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    , who underwent cesarean delivery and subsequently developed deep venous thrombosis (DVT) or pulmonary embolism (PE). These women were compared to a control group of women with obesity who underwent cesarean delivery but did not develop DVT or PE. Analysis of risk factors associated with VTE was performed using Chi-Square test and Fisher's exact test. We identified 43 VTE cases and 172 controls in the MFMU database. Increased risk of VTE was noted in women with endometritis (OR of 4.58 [95% CI: 1.86-11.2, P\u2009=\u2009.0004]), receiving a blood transfusion (OR 17.07 [95% CI: 4.46-65.3, P\u2009=\u2009.0001]), having a coagulopathy (OR 27.73 [95% CI: 3.24-237.25, P\u2009=\u2009.0003]), and urinary tract infection (OR 2.39 [95% CI: 1.08-5.28, P\u2009=\u2009.03]). Important risk factors for VTE in women with obesity who undergo cesarean delivery include endometritis, intra- or post-operative transfusion, coagulopathy, and urinary tract infection. The presence of one or more of these factors may help guide provider decision-making regarding whether to administer thromboprophylaxis.\n                  <\/jats:p>","DOI":"10.1177\/10760296241247203","type":"journal-article","created":{"date-parts":[[2024,4,15]],"date-time":"2024-04-15T12:13:15Z","timestamp":1713183195000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Venous Thromboembolism Risk Factors in Women With Obesity Who Undergo Cesarean Delivery"],"prefix":"10.1177","volume":"30","author":[{"given":"Tolulope B.","family":"Fatokun","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Cumberland Regional Hospital, Somerset, KY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah E.","family":"Swartz","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed","family":"Ebeid","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophia A.","family":"Cordes","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexis C.","family":"Gimovsky","sequence":"additional","affiliation":[{"name":"Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Brown University, Providence, RI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew D.","family":"Sparks","sequence":"additional","affiliation":[{"name":"Department of Biomedical Statistics, University of Vermont, Burlington, VT, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard L.","family":"Amdur","sequence":"additional","affiliation":[{"name":"Department of Surgery, Medical Faculty Associate, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0341-1086","authenticated-orcid":false,"given":"Homa K.","family":"Ahmadzia","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,4,15]]},"reference":[{"key":"bibr1-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000002114"},{"key":"bibr2-10760296241247203","volume":"19","author":"American College of Obstetricians and Gynecologists","year":"2011","journal-title":"ACOG Pract bull"},{"issue":"19","key":"bibr3-10760296241247203","first-page":"3953","volume":"121","author":"Sultan AA","year":"2013","journal-title":"Blood, J Am Soc Hematol"},{"key":"bibr4-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2016.06.026"},{"key":"bibr5-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2011.09.002"},{"key":"bibr6-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2005.11.008"},{"key":"bibr7-10760296241247203","unstructured":"Hales CM, Carroll MD, Fryar CD, Ogden CL. 2020. Prevalence of obesity and severe obesity among adults: United States, 2017\u20132018."},{"key":"bibr8-10760296241247203","volume":"9","author":"Kakkos SK","year":"2016","journal-title":"Cochrane Database Syst Rev."},{"key":"bibr9-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1111\/1471-0528.13706"},{"key":"bibr10-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2010.02847.x"},{"key":"bibr11-10760296241247203","volume":"196","author":"American College of Obstetricians and Gynecologists","year":"2018","journal-title":"ACOG Pract Bull"},{"key":"bibr12-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2300"},{"key":"bibr13-10760296241247203","unstructured":"RCOG. Reducing the risk of venous thromboembolism during pregnancy and the puerperium. Green-top Guideline No. 37a; 2015. https:\/\/www.rcog.org.uk\/media\/qejfhcaj\/gtg-37a.pdf"},{"key":"bibr14-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1097\/AOG.0000000000000007"},{"key":"bibr15-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-0528.2001.00004.x"},{"key":"bibr16-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1016\/j.jogn.2016.07.001"},{"key":"bibr17-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2019.03.008"},{"key":"bibr18-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096495"},{"key":"bibr19-10760296241247203","unstructured":"American College of Obstetricians and Gynecologists. Obesity in pregnancy.\n                      ACOG Practice bulletin no 156\n                      . 2015."},{"key":"bibr20-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70227-X"},{"key":"bibr21-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14568"},{"key":"bibr22-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2020.03.025"},{"key":"bibr23-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/4071892"},{"key":"bibr24-10760296241247203","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2014.944155"},{"key":"bibr25-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-014-3678-4"},{"key":"bibr26-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1055\/a-1717-7663"},{"key":"bibr27-10760296241247203","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinsp.2023.100230"}],"container-title":["Clinical and Applied Thrombosis\/Hemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10760296241247203","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10760296241247203","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10760296241247203","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:04:35Z","timestamp":1777385075000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10760296241247203"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,1]]},"references-count":27,"alternative-id":["10.1177\/10760296241247203"],"URL":"https:\/\/doi.org\/10.1177\/10760296241247203","relation":{},"ISSN":["1076-0296","1938-2723"],"issn-type":[{"value":"1076-0296","type":"print"},{"value":"1938-2723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,1]]},"article-number":"10760296241247203"}}