{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:10:38Z","timestamp":1777479038897,"version":"3.51.4"},"reference-count":33,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,1,1]],"date-time":"2024-01-01T00:00:00Z","timestamp":1704067200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2024,1]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To examine the effectiveness of rivaroxaban compared to enoxaparin in patients diagnosed with cancer and venous thromboembolism.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A search of Pub Med, Scopus, and Google Scholar, from inception through April 2023 was conducted. Articles comparing rivaroxaban with enoxaparin in patients with cancer and VTE\/PE\/DVT were included. Review Manager Version 5.2 was utilised for the analysis of the following outcomes; VTE, PE, DVT, major bleeding, and mortality.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>A total of 8 articles and 2276 patients were included in the final analysis. Pooled analysis showed that rivaroxaban had a statistically insignificant reduced association with VTE occurrence (RR:0.83, 95% CI:0.58\u20131.18, P:0.3) as well as a statically insignificant reduction in major bleeding (RR:0.79, 95% CI:0.53\u20131.18, P:0.25). Analysis showcased that there was an insignificant reduction of mortality rivaroxaban as compared to enoxaparin (RR:0.74, 95% CI: 0.46\u20131.20, P:0.23).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Rivaroxaban can serve as a viable alternative to enoxaparin, with no appreciable drawbacks, for preventing and managing VTE in patients with malignancy.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10760296241261364","type":"journal-article","created":{"date-parts":[[2024,6,13]],"date-time":"2024-06-13T14:30:31Z","timestamp":1718289031000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["Efficacy and Safety of Rivaroxaban Versus Enoxaparin in Prevention of Recurrence of Venous Thrombo-Embolism Events in Cancer Patients: A Meta-Analysis"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6411-8759","authenticated-orcid":false,"given":"Abdul Rafeh","family":"Awan","sequence":"first","affiliation":[{"name":"Department of Medicine, Nishtar Medical University, Multan, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abdullah","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Combined Military Hospital (CMH) Medical College, Lahore, \rPunjab"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Daniyal","sequence":"additional","affiliation":[{"name":"Combined Military Hospital (CMH) Medical College, Lahore, \rPunjab"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Malik Muhammad Hamza","family":"Khan","sequence":"additional","affiliation":[{"name":"Department of Medicine, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaikh Jehanzaib","family":"Saeed","sequence":"additional","affiliation":[{"name":"Department of Medicine, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad Bilal","family":"Siddiqui","sequence":"additional","affiliation":[{"name":"Department of Medicine, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sheraz","family":"Hakeem","sequence":"additional","affiliation":[{"name":"Department of Medicine, Aga Khan University, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Azka","family":"Shahab","sequence":"additional","affiliation":[{"name":"Department of Medicine, Bahria University Medical and Dental College, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Syed Hasham","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Medicine, Dow University of Health Sciences, Karachi, Pakistan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed Kamal","family":"Siddiqi","sequence":"additional","affiliation":[{"name":"Division of Cardiothoracic Imaging, Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,6,13]]},"reference":[{"key":"bibr1-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.6.585"},{"key":"bibr2-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa035451"},{"key":"bibr3-10760296241261364","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2015.0133"},{"key":"bibr4-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa025313"},{"key":"bibr5-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvn.2011.03.002"},{"key":"bibr6-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2015.12.025"},{"key":"bibr7-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1177\/1078155217690922"},{"key":"bibr8-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1177\/1078155217739683"},{"key":"bibr9-10760296241261364","unstructured":"Cochrane Handbook for Systematic Reviews of Interventions | Cochrane Training. 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The Cochrane Collaboration, 2020."},{"key":"bibr14-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.327.7414.557"},{"key":"bibr15-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1016\/j.mayocp.2021.04.026"},{"key":"bibr16-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.25604"},{"key":"bibr17-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1177\/1078155217718382"},{"key":"bibr18-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1186\/s12959-020-00221-2"},{"key":"bibr19-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1177\/10760296221132556"},{"key":"bibr20-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(14)70018-3"},{"key":"bibr21-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000017894"},{"key":"bibr22-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000011384"},{"key":"bibr23-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-022-00336-y"},{"key":"bibr24-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2018024893"},{"key":"bibr25-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.01461"},{"key":"bibr26-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13596"},{"key":"bibr27-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2022.55709"},{"key":"bibr28-10760296241261364","doi-asserted-by":"publisher","DOI":"10.1002\/jso.25113"},{"key":"bibr29-10760296241261364","unstructured":"Aamani Jupalli, Arshad Muhammad Iqbal. 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