{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,24]],"date-time":"2026-06-24T16:01:54Z","timestamp":1782316914546,"version":"3.54.5"},"reference-count":26,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,3,1]],"date-time":"2024-03-01T00:00:00Z","timestamp":1709251200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Research Physician Development Fund, Affiliated Hospital of Nantong University","award":["YJXYY202204-YSB05"],"award-info":[{"award-number":["YJXYY202204-YSB05"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2024,3]]},"abstract":"<jats:p>\n                    Post-thrombotic syndrome (PTS) is one of the most common long-term complications of lower extremity deep vein thrombosis (DVT). In order to study the long-term adverse prognosis of patients with DVT, explore the influencing factors for the prognosis of DVT, and provide a reliable reference for future research in the field of venous thrombosis, we collected and summarized information about the incidence of PTS, the PTS score and grading, the associated symptoms and drug-related adverse reactions in 501 patients with DVT. In our study, 54.1% of patients with DVT (271 of 501) experienced indications and manifestations of PTS, the male to female ratio was approximately 1:1. During the long-term follow up, the most common symptoms of PTS were anterior tibial edema and pain. By statistical analysis, we found that the outcome of thrombosis was the influencing factor of PTS score (1-4 points,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt;.05). The grading of PTS was primarily influenced by the history of varicose veins and DVT in the lower extremities. The duration of taking antithrombotic drugs affected the outcome of thrombosis (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt;.05), especially among the female patients. In addition, varied factors, such as lower extremity DVT complicated with pulmonary embolism and the duration of antithrombotic drug use were found to increase the chances of experiencing drug-related adverse reactions (odds ratio [OR]=2.798, 95% confidence interval [CI]: 1.413-5.541 \/ OR=2.778, 95% CI: 1.231-6.269). The above 2 factors were significant only among female patients with DVT (OR=4.03, 95% CI: 1.608-10.103 \/ OR=3.918, 95% CI: 1.123-13.669).\n                  <\/jats:p>","DOI":"10.1177\/10760296241266820","type":"journal-article","created":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T10:50:56Z","timestamp":1723632656000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Prognosis and Factors 4 to 10 Years After Deep Vein Thrombosis: A Long-Term Follow-up Cohort Study"],"prefix":"10.1177","volume":"30","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-6953-0645","authenticated-orcid":false,"given":"Jinhan","family":"Yao","sequence":"first","affiliation":[{"name":"Affliated Hospital of Nantong University"},{"name":"Medical College, Nantong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengru","family":"Han","sequence":"additional","affiliation":[{"name":"Affliated Hospital of Nantong University"},{"name":"Medical College, Nantong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jin","family":"Shi","sequence":"additional","affiliation":[{"name":"Affliated Hospital of Nantong University"},{"name":"Medical College, Nantong University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weina","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Shanghai Tenth People's Hospital"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, The Ninth People's Hospital of Suzhou"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6561-8598","authenticated-orcid":false,"given":"Yuquan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Affliated Hospital of Nantong University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,8,14]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2017.05.035"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.emc.2008.04.004"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.2174\/1381612828666220131094655"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2018-01-785956"},{"key":"e_1_3_2_6_2","unstructured":"Nasra K Negussie E. Sonography Vascular Peripheral Vein Assessment Protocols and Interpretation [M]. StatPearls. Treasure Island (FL) ineligible companies. Disclosure: Edsa Negussie declares no relevant financial relationships with ineligible companies.; StatPearls Publishing."},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s40477-020-00482-7"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.0246"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1177\/0268355516649333"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.23736\/S0392-9590.19.04084-7"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61902-9"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1615066"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1711-1263"},{"key":"e_1_3_2_14_2","first-page":"107602962094004","article-title":"The net clinical benefit of rivaroxaban compared to low-molecular-weight heparin in the treatment of cancer-associated thrombosis: systematic review and meta-analysis","volume":"27","author":"Mohamed MFH","year":"2021","unstructured":"Mohamed MFH, Elshafei MN, Ahmed MB, et al. The net clinical benefit of rivaroxaban compared to low-molecular-weight heparin in the treatment of cancer-associated thrombosis: systematic review and meta-analysis. Clin Appl Thromb Hemost. 2021;27:1076029620940046.","journal-title":"Clin Appl Thromb Hemost"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.4103\/0366-6999.206341"},{"key":"e_1_3_2_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvir.2012.07.030"},{"key":"e_1_3_2_17_2","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526\/a000776"},{"key":"e_1_3_2_18_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2023.1250480"},{"key":"e_1_3_2_19_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1660859"},{"key":"e_1_3_2_20_2","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0000000000000130"},{"key":"e_1_3_2_21_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.14346"},{"key":"e_1_3_2_22_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2021.07.055"},{"key":"e_1_3_2_23_2","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.84.s3.04"},{"key":"e_1_3_2_24_2","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.762443"},{"key":"e_1_3_2_25_2","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2020001830"},{"key":"e_1_3_2_26_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm9040923"},{"key":"e_1_3_2_27_2","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12180"}],"container-title":["Clinical and Applied Thrombosis\/Hemostasis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10760296241266820","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/10760296241266820","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/10760296241266820","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:04:41Z","timestamp":1777385081000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/10760296241266820"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,3]]},"references-count":26,"alternative-id":["10.1177\/10760296241266820"],"URL":"https:\/\/doi.org\/10.1177\/10760296241266820","relation":{},"ISSN":["1076-0296","1938-2723"],"issn-type":[{"value":"1076-0296","type":"print"},{"value":"1938-2723","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,3]]},"article-number":"10760296241266820"}}