{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:15:55Z","timestamp":1777479355698,"version":"3.51.4"},"reference-count":43,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To analyze 180-day survival and associated factors in patients with chronic kidney disease (CKD) who initiated anticoagulation therapy during hospitalization.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A survival analysis study was conducted using Kaplan-Meier curves on a retrospective cohort of CKD patients on anticoagulation. Cox regression identified factors associated with survival differences.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The study included 224 patients (50.90% male, 71.80%\u2009&gt;\u200965 years, 30.80% with atrial fibrillation (AF), and 50% with venous thromboembolism (VTE)). Mortality was 40.63%, with higher survival in the AF group versus VTE (p\u2009=\u20090.0107), CKD stage 3a versus stage 4 (p\u2009=\u20090.0009), and stage 5 versus stage 4 (p\u2009=\u20090.0277). Mortality risk was higher in patients with subsidized healthcare (HR 1.47; 95% CI 1.17\u20133.12; p\u2009=\u20090.010), cancer (HR 1.77; 95% CI 1.15-2.71; p\u2009=\u20090.008), and VTE (HR 1.87; 95% CI 1.22\u20132.86; p\u2009=\u20090.004), Arterial hypertension (HR 0.44; 95% CI 0.29-0.68; p\u2009=\u20090.001), coronary artery disease (HR 0.42; 95% CI 0.20-0.48; p\u2009=\u20090.022), and antiplatelet monotherapy (HR 0.56; 95% CI 0.32-0.96; p\u2009=\u20090.037) did not influence survival.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>CKD patients on anticoagulation therapy have high early mortality. Cancer, subsidized healthcare affiliation, and venous thromboembolism were independent risk factors associated with mortality, whereas hypertension and single antiplatelet therapy were not. This suggests that intensified follow-up and individualized management strategies may be particularly beneficial in these high-risk groups. Larger, prospective studies are needed to optimize anticoagulation management in this high-risk population.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10760296251405422","type":"journal-article","created":{"date-parts":[[2025,12,5]],"date-time":"2025-12-05T17:25:37Z","timestamp":1764955537000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Factors Associated with Different Survival Functions in Anticoagulated Patients with Chronic Kidney Disease"],"prefix":"10.1177","volume":"31","author":[{"given":"Diana Carolina","family":"Sandoval","sequence":"first","affiliation":[{"name":"Hospital Universitario San Ignacio"},{"name":"Department of Internal Medicine, Faculty of Medicine, Pontificia Universidad Javeriana, Bogot\u00e1, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4399-1062","authenticated-orcid":false,"given":"Paula Andrea","family":"Ruiz-Talero","sequence":"additional","affiliation":[{"name":"Hospital Universitario San Ignacio"},{"name":"Department of Internal Medicine, Faculty of Medicine, Pontificia Universidad Javeriana, Bogot\u00e1, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra Brigitte","family":"Amado","sequence":"additional","affiliation":[{"name":"Hospital Universitario San Ignacio"},{"name":"Department of Internal Medicine, Faculty of Medicine, Pontificia Universidad Javeriana, Bogot\u00e1, Colombia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Valentina","family":"Marulanda","sequence":"additional","affiliation":[{"name":"Hospital Universitario San Ignacio"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,12,5]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","unstructured":"Lv JC Zhang LX. 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