{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T16:15:55Z","timestamp":1777479355681,"version":"3.51.4"},"reference-count":32,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T00:00:00Z","timestamp":1754006400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Natural Science Foundation of Jurong Hospital Affiliated to Jiangsu University","award":["JY20231004"],"award-info":[{"award-number":["JY20231004"]}]},{"name":"Jurong City Urban Social Development Project","award":["ZA42112"],"award-info":[{"award-number":["ZA42112"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2025,8]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>To explore the impact of physical restraint (PR) on the occurrence of venous thromboembolism (VTE) in stroke patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Totally 321 stroke patients were randomly enrolled and categorized into 2 groups according to whether PR was used or not. Moreover, the effect of PR on VTE in stroke patients was explored, and the independent influencing factors for the occurrence of VTE in stroke patients were also identified.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Among the enrolled patients, 68 cases (21.18%) developed VTE, including 60 with muscular calf vein thrombosis, 6 with great saphenous vein thrombosis, and 2 with deep vein thrombosis (DVT). Of these 68 patients, 49 had cerebral infarction and 19 had intracerebral hemorrhage (ICH). Also, there were 39 patients (39\/96) developing VTE with PR, and 29 (29\/225) developing VTE without PR. Through analyzing the relationship between the incidence of VTE in stroke patients and clinicopathological parameters, it was discovered that diagnose (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200933.058 P\u2009=\u20090.000), history of diabetes (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200912.80 P\u2009=\u20090.000), muscle strength (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200921.608 P\u2009=\u20090.000), activity of daily living (ADL) (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200941.952 P\u2009=\u20090.000), and PR (\u03c7\n                      <jats:sup>2<\/jats:sup>\n                      \u2009=\u200931.004 P\u2009=\u20090.000) were significantly correlated with the occurrence of VTE. Moreover, as revealed by multivariate analysis of variance ICH (OR 4.485 (1.653\u201312.169), P\u2009=\u20090.003), previous history of diabetes (OR 2.511 (1.257\u20135.018), P\u2009=\u20090.009), low ADL (OR 0.208 (0.109\u20130.397), P\u2009=\u20090.000), and PR (OR 5.048 (2.520\u201310.113), P\u2009=\u20090.000) were the independent risk factors for VTE in stroke patients, while muscle strength (OR 0.679 (0.366\u20131.259), P\u2009=\u20090.219) had an impact on the occurrence of VTE, but was not an independent risk factor.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>This treatment center can lower the occurrence of VTE by standardizing the use of PR. Meanwhile, for the patients with ICH who have a history of diabetes and poor ADL, more education and care should be provided to minimize the occurrence of VTE.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10760296251408064","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T15:03:01Z","timestamp":1765551781000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Effect of Physical Restraint on the Occurrence of Venous Thromboembolism in Stroke Patients"],"prefix":"10.1177","volume":"31","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3399-0983","authenticated-orcid":false,"given":"Yue","family":"Hu","sequence":"first","affiliation":[{"name":"Department of Neurology, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-7474-6417","authenticated-orcid":false,"given":"Qin","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-3333-141X","authenticated-orcid":false,"given":"Zhangli","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Nursing, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianping","family":"Feng","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital with Nanjing Medical University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-6713-7842","authenticated-orcid":false,"given":"Lihua","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of hospital administration office, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-2237-1685","authenticated-orcid":false,"given":"Yi","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-1876-4187","authenticated-orcid":false,"given":"Chenlu","family":"Xu","sequence":"additional","affiliation":[{"name":"Department of Neurology, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-2852-8498","authenticated-orcid":false,"given":"Yan","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Neurology, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9169-1386","authenticated-orcid":false,"given":"Hui","family":"Yang","sequence":"additional","affiliation":[{"name":"Department of Nursing, Jurong Hospital Affiliated to Jiangsu University, Zhenjiang, Jiangsu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,12,12]]},"reference":[{"key":"e_1_3_4_2_2","unstructured":"Britannica. 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