{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:00:09Z","timestamp":1780732809979,"version":"3.54.1"},"reference-count":22,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Clin Appl Thromb Hemost"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>This study aimed to compare the efficacy of mechanical thrombus clearance combined with stenting versus direct stenting alone in patients with iliofemoral venous disease,, and to analyze the characteristics of different diagnostic subgroups among non-thrombotic patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A retrospective analysis was conducted on 137 patients who underwent iliac vein stent implantation between January 2020 and March 2025. Based on the presence of acute\/subacute thrombosis and surgical strategy, patients were divided into a Thrombus Treatment Group (Angiojet thrombus aspiration + stenting, n=87) and a Non-Thrombotic Treatment Group (direct stenting, n=50). Within the Non-Thrombotic Group, further stratification yielded Subgroup A (pure iliac vein compression syndrome, n=29) and Subgroup B (associated thrombotic disease, e.g., post-thrombotic syndrome, n=21). Baseline characteristics, perioperative data, and 3-6 month follow-up outcomes were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Patients in the Thrombus Treatment Group were older (70.2\u00b111.4 vs. 62.1\u00b17.2 years, P&lt;0.001), required fewer stents (1.3\u00b10.6 vs. 1.8\u00b10.9, P&lt;0.001), but had longer procedure times (122.7\u00b138.3 vs. 87.8\u00b151.3 minutes, P&lt;0.001). No significant differences were found between the two main groups in post-operative ultrasound patency rates (69.1% vs. 59.1%, P=0.243) or adverse event rates (2.5% vs. 6.8%, P=0.224). Subgroup analysis revealed that compared to Subgroup A, Subgroup B had a higher prevalence of prior DVT history (47.6% vs. 0%, P&lt;0.001) and pre-operative swelling symptoms (81.0% vs. 6.9%, P&lt;0.001), and required more complex procedures (stent use: 2.3\u00b11.0 vs. 1.5\u00b10.7, P&lt;0.001). However, short-term follow-up outcomes were similar between the subgroups.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>For iliofemoral venous disease with concomitant thrombosis, a strategy of thrombus clearance combined with selective stenting can reduce stent usage while achieving short-term efficacy comparable to direct stenting alone in its respective clinical context. Among non-thrombotic patients, the subgroup with thrombosis-related disease presents distinct clinical features and higher procedural complexity, yet still benefits from endovascular reconstruction.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/10760296261458518","type":"journal-article","created":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T05:56:48Z","timestamp":1780466208000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Comparative Analysis of Two Strategies for Iliac Vein Stenting: Thrombus Clearance-Assisted Versus Direct Stenting"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2306-4176","authenticated-orcid":false,"given":"Guili","family":"Wang","sequence":"first","affiliation":[{"name":"Central Hospital Affiliated to Shandong First Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nuan","family":"Wen","sequence":"additional","affiliation":[{"name":"Central Hospital Affiliated to Shandong First Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lifeng","family":"Qu","sequence":"additional","affiliation":[{"name":"Central Hospital Affiliated to Shandong First Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donglin","family":"Lu","sequence":"additional","affiliation":[{"name":"Central Hospital Affiliated to Shandong First Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiwen","family":"Liu","sequence":"additional","affiliation":[{"name":"Central Hospital Affiliated to Shandong First Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoxuan","family":"Liu","sequence":"additional","affiliation":[{"name":"Central Hospital Affiliated to Shandong First Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,6,2]]},"reference":[{"key":"e_1_3_4_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2006.06200.x"},{"key":"e_1_3_4_3_2","doi-asserted-by":"publisher","DOI":"10.1080\/13645706.2019.1580748"},{"key":"e_1_3_4_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2020.02.011"},{"key":"e_1_3_4_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(19)30209-1"},{"key":"e_1_3_4_6_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-022-01714-9"},{"key":"e_1_3_4_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/15533506231169168"},{"key":"e_1_3_4_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.avsg.2013.05.001"},{"key":"e_1_3_4_9_2","doi-asserted-by":"publisher","DOI":"10.23736\/S0392-9590.21.04663-0"},{"issue":"2","key":"e_1_3_4_10_2","first-page":"53","article-title":"European Society for Vascular Surgery (ESVS) 2022 clinical practice guidelines on the management of chronic venous disease of the lower limbs","volume":"47","author":"Nyamekye IK","year":"2022","unstructured":"Nyamekye IK. European Society for Vascular Surgery (ESVS) 2022 clinical practice guidelines on the management of chronic venous disease of the lower limbs. J Med Vasc. 2022;47(2):53-55.","journal-title":"J Med Vasc"},{"key":"e_1_3_4_11_2","doi-asserted-by":"publisher","DOI":"10.1177\/1076029618821190"},{"key":"e_1_3_4_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(14)70018-3"},{"key":"e_1_3_4_13_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2009.08.032"},{"key":"e_1_3_4_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2007.09.043"},{"key":"e_1_3_4_15_2","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X16650747"},{"key":"e_1_3_4_16_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejvs.2015.02.007"},{"key":"e_1_3_4_17_2","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-149-10-200811180-00004"},{"key":"e_1_3_4_18_2","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(15)00248-3"},{"key":"e_1_3_4_19_2","doi-asserted-by":"publisher","DOI":"10.1024\/0301-1526\/a001141"},{"key":"e_1_3_4_20_2","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019002364"},{"issue":"4","key":"e_1_3_4_21_2","first-page":"748","article-title":"Endovascular management of the deep venous thrombosis: A new challenging role for the endovascular specialist in 2020","volume":"98","author":"Midulla M","year":"2021","unstructured":"Midulla M, Chevallier O, Comby PO, et al. Endovascular management of the deep venous thrombosis: A new challenging role for the endovascular specialist in 2020. 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