{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T14:59:32Z","timestamp":1784818772390,"version":"3.55.0"},"reference-count":30,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T00:00:00Z","timestamp":1773446400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2026,5,1]]},"abstract":"<jats:p>\n                    Biliary tract infections (BTI) are common intra-abdominal infections associated with significant morbidity and mortality. We aimed to evaluate the causative agents of BTIs, their resistance profiles, and factors associated with resistant infections and mortality. This retrospective study included patients aged \u226518 years who had bile cultures obtained for BTI between January 2022 and January 2024 in a tertiary health-care center. A total of 148 bile cultures from 101 patients were analyzed. Pathogens were identified in 73% of the cultures;\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    and\n                    <jats:italic toggle=\"yes\">Enterococcus<\/jats:italic>\n                    spp. were the most common pathogens. Extended-spectrum \u03b2-lactamase (ESBL) production was detected in 37.3% of\n                    <jats:italic toggle=\"yes\">Enterobacterales<\/jats:italic>\n                    isolates, and ampicillin resistance was observed in 50% of enterococci. Among all identified pathogens, 31 (28.7%) were resistant microorganisms. The 30-day mortality rate was 13% and was significantly higher in patients with resistant infection, health care-associated infection, or malignancy. In multivariate analysis, resistant infections were associated with an eightfold increase in mortality. Currently antimicrobial resistance is becoming one of the leading causes of death. Resistant pathogens were frequently identified, even in community-acquired infections, and were associated with a significant increase in mortality. It is crucial to identify factors influencing resistant infections and mortality for optimizing empirical treatment strategies.\n                  <\/jats:p>","DOI":"10.1177\/10766294261431302","type":"journal-article","created":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T10:15:03Z","timestamp":1773483303000},"page":"151-157","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Antimicrobial Resistance on Outcomes in Biliary Tract Infections: A Retrospective Study from a Tertiary Care Center"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4500-8594","authenticated-orcid":false,"given":"Aybeg\u00fcm","family":"\u00d6z\u015fahin","sequence":"first","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Recep Tayyip Erdo\u011fan University Training and Research Hospital, Rize, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuba","family":"\u0130lgar","sequence":"additional","affiliation":[{"name":"Department of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, Recep Tayyip Erdo\u011fan University, Rize, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zehra Zeynep","family":"Keklikk\u0131ran","sequence":"additional","affiliation":[{"name":"Training and Research Hospital, Gastrointestinal Surgery, Recep Tayyip Erdo\u011fan University Training and Research Hospital, Rize, T\u00fcrkiye."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,3,14]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-021-00387-8"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.5772\/intechopen.100063"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2022.2350"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-82603-8"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10123-022-00251-y"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.4274\/mjima.2016.7"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.9790\/6718-03105862"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2020.07.048"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkac162"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciae403"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-023-05604-0"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/HEP.0000000000000264"},{"key":"e_1_3_3_14_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-3402016"},{"key":"e_1_3_3_15_2","doi-asserted-by":"publisher","DOI":"10.1093\/gastro\/goae010"},{"key":"e_1_3_3_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/jhbp.518"},{"key":"e_1_3_3_17_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-020-01201-6"},{"key":"e_1_3_3_18_2","doi-asserted-by":"publisher","DOI":"10.3947\/ic.2022.0156"},{"key":"e_1_3_3_19_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13017-016-0089-y"},{"key":"e_1_3_3_20_2","doi-asserted-by":"publisher","DOI":"10.5152\/kd.2019.84"},{"key":"e_1_3_3_21_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0043-1771332"},{"key":"e_1_3_3_22_2","doi-asserted-by":"publisher","DOI":"10.1089\/sur.2016.261"},{"key":"e_1_3_3_23_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-1790-1314"},{"key":"e_1_3_3_24_2","volume-title":"Antimicrobial resistance surveillance in Europe 2023\u20132021 data","year":"2023","unstructured":"Antimicrobial resistance surveillance in Europe 2023\u20132021 data. European Centre for Disease Control and Prevention & World Health Organisation; 2023."},{"key":"e_1_3_3_25_2","doi-asserted-by":"publisher","DOI":"10.1155\/2022\/9255444"},{"key":"e_1_3_3_26_2","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkn514"},{"key":"e_1_3_3_27_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-020-06820-3"},{"key":"e_1_3_3_28_2","doi-asserted-by":"publisher","DOI":"10.1055\/a-2230-8229"},{"key":"e_1_3_3_29_2","doi-asserted-by":"publisher","DOI":"10.5455\/annalsmedres.2020.05.516"},{"key":"e_1_3_3_30_2","doi-asserted-by":"publisher","DOI":"10.1080\/00365521.2021.1902558"},{"issue":"3","key":"e_1_3_3_31_2","article-title":"Complicated \u0131ntraabdominal \u0131nfections; epidemiology of microorganisms, resistance profiles and risk factors associated with mortality","volume":"57","author":"Ucer \u015e","year":"2024","unstructured":"Ucer \u015e, , Baykam N. Complicated \u0131ntraabdominal \u0131nfections; epidemiology of microorganisms, resistance profiles and risk factors associated with mortality. 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