{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,23]],"date-time":"2026-10-23T20:34:54Z","timestamp":1792787694403,"version":"4.5.0"},"reference-count":27,"publisher":"SAGE Publications","issue":"11","license":[{"start":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T00:00:00Z","timestamp":1784764800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Animal and Plant Quarantine Agency","award":["Z-1543061-2021-23-02"],"award-info":[{"award-number":["Z-1543061-2021-23-02"]}],"id":[{"id":"https:\/\/ror.org\/04sbe6g90","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Microbial Drug Resistance"],"published-print":{"date-parts":[[2026,11,1]]},"abstract":"<jats:p>\n                    This study evaluated a 6-month, on-farm antimicrobial stewardship model integrating veterinary oversight, appropriate antimicrobial use, enhanced biosecurity, and an all-in\/all-out system on five Korean pig farms lacking prior oversight. Antimicrobial usage and resistance of\n                    <jats:italic toggle=\"yes\">Escherichia coli<\/jats:italic>\n                    were compared before and after implementation. The number of antimicrobial prescriptions decreased significantly following the implementation of the model (from 15.2 \u00b1 9.2 to 7.2 \u00b1 4.7). After model implementation, prescriptions for suckling piglets decreased from 2.2 \u00b1 1.6 to 0.4 \u00b1 0.9, and for weaned piglets from 4.4 \u00b1 2.4 to 1.8 \u00b1 1.1. Overall antimicrobial resistance decreased following model implementation, with the largest decreases were observed in ciprofloxacin (from 57.3% to 21.9%), nalidixic acid (from 60.0% to 34.2%), and cefazolin (from 92.0% to 64.4%). The multidrug-resistance rates in eight antimicrobial classes decreased significantly across all stages (from 28.0% to 4.1%), with decreases for suckling piglets (from 33.3% to 7.1%), weaned piglets (from 40.0% to 0.0%), growers (from 26.7% to 0.0%), finishers (from 26.7% to 14.3%), and sows (from 13.3% to 0.0%). The model effectively reduced both antimicrobial use and resistance, supporting its value for antimicrobial stewardship in pig production.\n                  <\/jats:p>","DOI":"10.1177\/10766294261473085","type":"journal-article","created":{"date-parts":[[2026,7,23]],"date-time":"2026-07-23T12:31:38Z","timestamp":1784809898000},"page":"488-494","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["On-Farm Implementation of an Integrated Antimicrobial Stewardship Model in Pig Production: Effects on Antimicrobial Use and Resistance"],"prefix":"10.1177","volume":"32","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6080-0374","authenticated-orcid":false,"given":"Kyung-Hyo","family":"Do","sequence":"first","affiliation":[{"name":"College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea."},{"name":"Department of Companion Animal Health, Daegu Haany University, Gyeongsan, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da-Hye","family":"Ryu","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min-Gyu","family":"Kim","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Jung","family":"Ahn","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chang Min","family":"Jung","sequence":"additional","affiliation":[{"name":"Onnuri Animal Hospital, Cheonan, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Won","family":"Lee","sequence":"additional","affiliation":[{"name":"Boehringer Ingelheim Animal Health Korea Ltd., Seoul, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suk-Kyung","family":"Lim","sequence":"additional","affiliation":[{"name":"Animal and Plant Quarantine Agency, Ministry of Agriculture, Food and Rural Affairs, Gimcheon, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyun-Mi","family":"Kang","sequence":"additional","affiliation":[{"name":"Animal and Plant Quarantine Agency, Ministry of Agriculture, Food and Rural Affairs, Gimcheon, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kwang-Won","family":"Seo","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wan-Kyu","family":"Lee","sequence":"additional","affiliation":[{"name":"College of Veterinary Medicine, Chungbuk National University, Cheongju, Republic of Korea."}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2026,7,23]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12866-022-02604-z"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics9110755"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.prevetmed.2021.105408"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.14405\/kjvr.2020.60.3.163"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1111\/1477-9552.12439"},{"issue":"04","key":"e_1_3_2_7_1","first-page":"519","article-title":"Antimicrobial Resistance, Adhesin and toxin genes of porcine pathogenic Escherichia coli following the ban on antibiotics as the growth promoters in feed","volume":"41","author":"Do K-H","year":"2021","unstructured":"6.Do K-H, , Byun J-W, , Lee W-K. Antimicrobial Resistance, Adhesin and toxin genes of porcine pathogenic Escherichia coli following the ban on antibiotics as the growth promoters in feed. Pak Vet J 2021;41(04):519\u2013523; doi: 10.29261\/pakvetj\/2021.067","journal-title":"Pak Vet J"},{"issue":"2","key":"e_1_3_2_8_1","first-page":"873","article-title":"Comparative analysis of biosecurity practices, antimicrobial usage and antimicrobial resistance in Korean pig farms by farm type","volume":"45","author":"Do K-H","year":"2025","unstructured":"7.Do K-H, , Choe S-J, , Jung CM, et al. Comparative analysis of biosecurity practices, antimicrobial usage and antimicrobial resistance in Korean pig farms by farm type. Pak Vet J 2025;45(2):873\u2013879; doi: 10.29261\/pakvetj\/2025.199","journal-title":"Pak Vet J"},{"key":"e_1_3_2_9_1","volume-title":"Development of Model to Use Antimicrobials in Medically Efficient Way in Broilers and Pigs","author":"Lee YJ","year":"2023","unstructured":"8.Lee YJ. 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